Protein: ELF2
ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)

Gene: ELF2
Organism: Homo sapiens
Interactions: 148
UniProt ID: Q15723

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

954480

PRPS1
Ribose-phosphate pyrophosphokinase 1

3

5

High-throughput

0.667

High

998356

H31
Histone H3.1

3

12

High-throughput

0.640

High

610338

PRS6A
26S proteasome regulatory subunit 6A

3

0

High-throughput

0.638

High

960434

PSME3
Proteasome activator complex subunit 3

3

0

High-throughput

0.638

High

1029845

RUNX1
Runt-related transcription factor 1

2

4

Small-scale

0.629

High

1152742

IKZF5
Zinc finger protein Pegasus

2

1

High-throughput

0.628

High

685202

PAX6
Paired box protein Pax-6

1

6

High-throughput

0.618

High

738985

ELF1
ETS-related transcription factor Elf-1

1

15

High-throughput

0.618

High

1017425

FOXK1
Forkhead box protein K1

1

14

High-throughput

0.618

High

1055606

GABPA
GA-binding protein alpha chain

1

18

High-throughput

0.618

High

1152727

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

9

High-throughput

0.618

High

1152732

ELF4
ETS-related transcription factor Elf-4

1

16

High-throughput

0.618

High

1152745

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

9

High-throughput

0.618

High

212407

SPIT2
Kunitz-type protease inhibitor 2

3

12

High-throughput

0.609

High

1152751

HPBP1
Hsp70-binding protein 1

3

1

High-throughput

0.609

High

1152713

NF2IP
NFATC2-interacting protein

2

0

High-throughput

0.602

High

474013

NFIC
Nuclear factor 1 C-type

2

20

High-throughput

0.595

High

175892

SET1A
Histone-lysine N-methyltransferase SETD1A

2

20

High-throughput

0.584

High

372123

MYC
Myc proto-oncogene protein

2

19

High-throughput

0.584

High

980792

H2B1C
Histone H2B type 1-C/E/F/G/I

2

12

High-throughput

0.584

High

1087760

NFIA
Nuclear factor 1 A-type

2

20

High-throughput

0.584

High

1133427

NFIX
Nuclear factor 1 X-type

2

20

High-throughput

0.584

High

1152754

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

2

13

High-throughput

0.584

High

1152719

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

2

5

Small-scale

0.571

High

1152766

ZBT32
Zinc finger and BTB domain-containing protein 32

1

1

High-throughput

0.541

High

549598

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

5

High-throughput

0.536

High

1115676

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.536

High

1152724

AJUBA
LIM domain-containing protein ajuba

1

8

High-throughput

0.536

High

1152765

AR2BP
ADP-ribosylation factor-like protein 2-binding protein

1

1

High-throughput

0.536

High

422157

A4
Amyloid-beta precursor protein

1

12

High-throughput

0.501

High

351781

LGI1
Leucine-rich glioma-inactivated protein 1

1

1

High-throughput

0.489

High

1152730

TCPQM
T-complex protein 1 subunit theta-like 2

1

2

High-throughput

0.489

High

143013

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

190925

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

5

High-throughput

0.479

High

274333

SIN3B
Paired amphipathic helix protein Sin3b

1

4

High-throughput

0.479

High

282724

E2F6
Transcription factor E2F6

1

5

High-throughput

0.479

High

339757

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

385777

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

3

High-throughput

0.479

High

406222

MYCN
N-myc proto-oncogene protein

1

12

High-throughput

0.479

High

463536

LYN
Tyrosine-protein kinase Lyn

1

4

Small-scale

0.479

High

487354

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

519511

MYBB
Myb-related protein B

1

6

High-throughput

0.479

High

520082

ANDR
Androgen receptor

1

15

High-throughput

0.479

High

559765

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

11

High-throughput

0.479

High

576232

PO2F1
POU domain, class 2, transcription factor 1

1

12

High-throughput

0.479

High

586299

ZEP1
Zinc finger protein 40

1

6

High-throughput

0.479

High

613052

EGR1
Early growth response protein 1

1

8

High-throughput

0.479

High

628791

TBP
TATA-box-binding protein

1

3

High-throughput

0.479

High

675516

TYY1
Transcriptional repressor protein YY1

1

9

High-throughput

0.479

High

711768

ARI4A
AT-rich interactive domain-containing protein 4A

1

20

High-throughput

0.479

High

711822

KDM5A
Lysine-specific demethylase 5A

1

10

High-throughput

0.479

High

714150

PML
Protein PML

1

17

High-throughput

0.479

High

790053

ZEB1
Zinc finger E-box-binding homeobox 1

1

4

High-throughput

0.479

High

833952

HNF4A
Hepatocyte nuclear factor 4-alpha

1

9

High-throughput

0.479

High

872365

SOX2
Transcription factor SOX-2

1

18

Small-scale

0.479

High

879133

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

11

High-throughput

0.479

High

883549

CENPA
Histone H3-like centromeric protein A

1

12

High-throughput

0.479

High

886894

CEBPA
CCAAT/enhancer-binding protein alpha

1

12

High-throughput

0.479

High

892029

TAF6
Transcription initiation factor TFIID subunit 6

1

4

High-throughput

0.479

High

895719

LHX2
LIM/homeobox protein Lhx2

1

6

High-throughput

0.479

High

913775

ZN131
Zinc finger protein 131

1

5

High-throughput

0.479

High

913882

ZN143
Zinc finger protein 143

1

2

High-throughput

0.479

High

927315

ATX1
Ataxin-1

1

8

High-throughput

0.479

High

944659

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.479

High

979722

H4
Histone H4

1

2

High-throughput

0.479

High

1016890

H33
Histone H3.3

1

12

High-throughput

0.479

High

1041535

KMT2A
Histone-lysine N-methyltransferase 2A

1

20

High-throughput

0.479

High

1053293

MBTD1
MBT domain-containing protein 1

1

11

High-throughput

0.479

High

1055022

MEF2C
Myocyte-specific enhancer factor 2C

1

6

High-throughput

0.479

High

1086769

BPTF
Nucleosome-remodeling factor subunit BPTF

1

20

High-throughput

0.479

High

1097310

CBX3
Chromobox protein homolog 3

1

2

High-throughput

0.479

High

1130054

SMC1A
Structural maintenance of chromosomes protein 1A

1

6

High-throughput

0.479

High

1145464

RBBP5
Retinoblastoma-binding protein 5

1

10

High-throughput

0.479

High

1149768

TAF5
Transcription initiation factor TFIID subunit 5

1

11

High-throughput

0.479

High

1152693

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

5

High-throughput

0.479

High

1152694

TAF12
Transcription initiation factor TFIID subunit 12

1

2

High-throughput

0.479

High

1152695

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

1152696

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

6

High-throughput

0.479

High

1152698

TAF3
Transcription initiation factor TFIID subunit 3

1

20

High-throughput

0.479

High

1152699

LIN54
Protein lin-54 homolog

1

3

High-throughput

0.479

High

1152700

TAF2
Transcription initiation factor TFIID subunit 2

1

3

High-throughput

0.479

High

1152701

NFRKB
Nuclear factor related to kappa-B-binding protein

1

18

High-throughput

0.479

High

1152702

SRCAP
Helicase SRCAP

1

20

High-throughput

0.479

High

1152703

ASXL2
Putative Polycomb group protein ASXL2

1

20

High-throughput

0.479

High

1152704

KANL1
KAT8 regulatory NSL complex subunit 1

1

2

High-throughput

0.479

High

1152705

POGZ
Pogo transposable element with ZNF domain

1

3

High-throughput

0.479

High

1152706

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

20

High-throughput

0.479

High

1152708

MGAP
MAX gene-associated protein

1

7

High-throughput

0.479

High

1152709

ASXL1
Polycomb group protein ASXL1

1

6

High-throughput

0.479

High

1152710

SMC5
Structural maintenance of chromosomes protein 5

1

3

High-throughput

0.479

High

1152714

NUP43
Nucleoporin Nup43

1

10

High-throughput

0.479

High

1152716

SP7
Transcription factor Sp7

1

20

High-throughput

0.479

High

1152717

GATD1
GATA zinc finger domain-containing protein 1

1

3

High-throughput

0.479

High

1152718

TOPB1
DNA topoisomerase 2-binding protein 1

1

7

High-throughput

0.479

High

1152720

ESR2
Estrogen receptor beta

1

15

High-throughput

0.479

High

1152721

LHX4
LIM/homeobox protein Lhx4

1

6

High-throughput

0.479

High

1152722

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

11

High-throughput

0.479

High

1152723

MCRS1
Microspherule protein 1

1

2

High-throughput

0.479

High

1152725

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

12

High-throughput

0.479

High

1152726

ZFP91
E3 ubiquitin-protein ligase ZFP91

1

3

High-throughput

0.479

High

1152728

EP400
E1A-binding protein p400

1

20

High-throughput

0.479

High

1152729

PHF12
PHD finger protein 12

1

20

High-throughput

0.479

High

1152733

DDA1
DET1- and DDB1-associated protein 1

1

2

High-throughput

0.479

High

1152734

KLF16
Krueppel-like factor 16

1

20

High-throughput

0.479

High

1152735

ARP6
Actin-related protein 6

1

6

High-throughput

0.479

High

1152737

SP130
Histone deacetylase complex subunit SAP130

1

12

High-throughput

0.479

High

1152738

BRD8
Bromodomain-containing protein 8

1

20

High-throughput

0.479

High

1152739

ING2
Inhibitor of growth protein 2

1

5

High-throughput

0.479

High

1152740

EPC1
Enhancer of polycomb homolog 1

1

3

High-throughput

0.479

High

1152741

ZN644
Zinc finger protein 644

1

8

High-throughput

0.479

High

1152743

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

6

High-throughput

0.479

High

1152744

KAT8
Histone acetyltransferase KAT8

1

8

High-throughput

0.479

High

1152746

KANL2
KAT8 regulatory NSL complex subunit 2

1

2

High-throughput

0.479

High

1152747

BRMS1
Breast cancer metastasis-suppressor 1

1

6

High-throughput

0.479

High

1152748

SHCAF
SIN3-HDAC complex-associated factor

1

1

High-throughput

0.479

High

1152750

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

1152752

CXXC1
CXXC-type zinc finger protein 1

1

20

High-throughput

0.479

High

1152753

KANL3
KAT8 regulatory NSL complex subunit 3

1

2

High-throughput

0.479

High

1152755

MO4L1
Mortality factor 4-like protein 1

1

2

High-throughput

0.479

High

1152756

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1152757

ING1
Inhibitor of growth protein 1

1

12

High-throughput

0.479

High

1152758

GMEB2
Glucocorticoid modulatory element-binding protein 2

1

4

High-throughput

0.479

High

1152759

INO80
Chromatin-remodeling ATPase INO80

1

20

High-throughput

0.479

High

1152760

KMT2B
Histone-lysine N-methyltransferase 2B

1

20

High-throughput

0.479

High

1152761

PHF8
Histone lysine demethylase PHF8

1

15

High-throughput

0.479

High

1152762

ZN148
Zinc finger protein 148

1

10

High-throughput

0.479

High

1152764

ZN281
Zinc finger protein 281

1

10

High-throughput

0.479

High

1152767

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

1152768

TRRAP
Transformation/transcription domain-associated protein

1

7

High-throughput

0.479

High

1152769

KLF12
Krueppel-like factor 12

1

20

High-throughput

0.479

High

1152770

HCFC2
Host cell factor 2

1

5

High-throughput

0.479

High

1152771

ZHX2
Zinc fingers and homeoboxes protein 2

1

9

High-throughput

0.479

High

697127

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

703147

TEAD1
Transcriptional enhancer factor TEF-1

1

0

High-throughput

0.458

High

799902

COIL
Coilin

1

0

High-throughput

0.458

High

1152697

LIN9
Protein lin-9 homolog

1

0

High-throughput

0.458

High

1152707

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1152712

BANP
Protein BANP

1

0

High-throughput

0.458

High

1152715

ZN507
Zinc finger protein 507

1

0

High-throughput

0.458

High

1152749

ZBT40
Zinc finger and BTB domain-containing protein 40

1

0

High-throughput

0.458

High

1152763

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

299211

FLOT1
Flotillin-1

1

10

High-throughput

0.457

High

231579

PRKY
Putative serine/threonine-protein kinase PRKY

1

2

High-throughput

0.445

High

1152711

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.445

High

1152731

CDC5L
Cell division cycle 5-like protein

1

6

High-throughput

0.445

High

596484

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.279

Low

991851

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.249

Low

1152736

CF062
Uncharacterized protein C6orf62

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025