Protein: ELF1
ETS-related transcription factor Elf-1 (E74-like factor 1)

Gene: ELF1
Organism: Homo sapiens
Interactions: 137
UniProt ID: P32519

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001817 - regulation of cytokine production

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

626093

NFKB1
Nuclear factor NF-kappa-B p105 subunit

2

11

Small-scale

0.822

High

738970

REL
Proto-oncogene c-Rel

2

15

Small-scale

0.819

High

340835

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

18

Small-scale

0.618

High

738966

FOXK1
Forkhead box protein K1

1

16

High-throughput

0.618

High

738967

FOXK2
Forkhead box protein K2

1

14

High-throughput

0.618

High

738972

GABPA
GA-binding protein alpha chain

1

16

High-throughput

0.618

High

738975

FOXC1
Forkhead box protein C1

1

14

High-throughput

0.618

High

738977

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

15

Small-scale

0.618

High

738985

ELF2
ETS-related transcription factor Elf-2

1

15

High-throughput

0.618

High

739021

FEV
Protein FEV

1

16

High-throughput

0.618

High

738979

NFYC
Nuclear transcription factor Y subunit gamma

2

1

High-throughput

0.606

High

738974

NFIA
Nuclear factor 1 A-type

2

20

High-throughput

0.584

High

738982

NFIX
Nuclear factor 1 X-type

2

20

High-throughput

0.584

High

739038

HPBP1
Hsp70-binding protein 1

2

1

High-throughput

0.567

High

601573

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

Small-scale

0.554

High

464836

SP1
Transcription factor Sp1

1

20

Small-scale

0.552

High

738987

NF2L2
Nuclear factor erythroid 2-related factor 2

1

20

Small-scale

0.541

High

738980

FHL2
Four and a half LIM domains protein 2

1

3

High-throughput

0.536

High

739047

AR2BP
ADP-ribosylation factor-like protein 2-binding protein

1

1

High-throughput

0.536

High

442612

RB
Retinoblastoma-associated protein

1

2

Small-scale

0.534

High

725173

HXC13
Homeobox protein Hox-C13

1

15

Small-scale

0.534

High

738968

RUNX1
Runt-related transcription factor 1

1

4

Small-scale

0.501

High

739011

KLHL6
Kelch-like protein 6

1

4

High-throughput

0.489

High

659658

NFYA
Nuclear transcription factor Y subunit alpha

1

0

Small-scale

0.480

High

65703

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

3

High-throughput

0.479

High

130705

TAF4
Transcription initiation factor TFIID subunit 4

1

15

High-throughput

0.479

High

142864

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

175848

SET1A
Histone-lysine N-methyltransferase SETD1A

1

20

High-throughput

0.479

High

180723

TIF1A
Transcription intermediary factor 1-alpha

1

20

High-throughput

0.479

High

282678

E2F6
Transcription factor E2F6

1

6

High-throughput

0.479

High

283437

TAD2A
Transcriptional adapter 2-alpha

1

19

High-throughput

0.479

High

339668

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

340299

YETS4
YEATS domain-containing protein 4

1

1

High-throughput

0.479

High

370582

FOS
Protein c-Fos

1

14

Small-scale

0.479

High

371294

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

424147

S10A8
Protein S100-A8

1

6

High-throughput

0.479

High

429383

JUN
Transcription factor Jun

1

17

Small-scale

0.479

High

463368

LYN
Tyrosine-protein kinase Lyn

1

4

Small-scale

0.479

High

473820

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

505524

ATX1L
Ataxin-1-like

1

10

High-throughput

0.479

High

559731

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

13

High-throughput

0.479

High

584001

FOSL1
Fos-related antigen 1

1

9

Small-scale

0.479

High

584069

FOSL2
Fos-related antigen 2

1

7

Small-scale

0.479

High

586234

ZEP1
Zinc finger protein 40

1

7

High-throughput

0.479

High

603619

JUNB
Transcription factor JunB

1

20

Small-scale

0.479

High

605052

JUND
Transcription factor JunD

1

15

Small-scale

0.479

High

617079

ATF1
Cyclic AMP-dependent transcription factor ATF-1

1

7

High-throughput

0.479

High

628713

TBP
TATA-box-binding protein

1

3

High-throughput

0.479

High

639675

TAF1
Transcription initiation factor TFIID subunit 1

1

20

High-throughput

0.479

High

675382

TYY1
Transcriptional repressor protein YY1

1

10

High-throughput

0.479

High

738957

CEBPA
CCAAT/enhancer-binding protein alpha

1

10

High-throughput

0.479

High

738958

TAF6
Transcription initiation factor TFIID subunit 6

1

5

High-throughput

0.479

High

738959

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

20

High-throughput

0.479

High

738960

ZN131
Zinc finger protein 131

1

7

High-throughput

0.479

High

738961

FOSB
Protein FosB

1

20

Small-scale

0.479

High

738962

RBM11
Splicing regulator RBM11

1

4

High-throughput

0.479

High

738963

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.479

High

738964

H2B1C
Histone H2B type 1-C/E/F/G/I

1

12

High-throughput

0.479

High

738965

H33
Histone H3.3

1

13

High-throughput

0.479

High

738969

KMT2A
Histone-lysine N-methyltransferase 2A

1

20

High-throughput

0.479

High

738971

MBTD1
MBT domain-containing protein 1

1

12

High-throughput

0.479

High

738973

BPTF
Nucleosome-remodeling factor subunit BPTF

1

20

High-throughput

0.479

High

738978

PWP1
Periodic tryptophan protein 1 homolog

1

20

High-throughput

0.479

High

738981

SMC1A
Structural maintenance of chromosomes protein 1A

1

6

High-throughput

0.479

High

738983

RBBP5
Retinoblastoma-binding protein 5

1

12

High-throughput

0.479

High

738984

TAF5
Transcription initiation factor TFIID subunit 5

1

16

High-throughput

0.479

High

738986

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

6

High-throughput

0.479

High

738988

TAF12
Transcription initiation factor TFIID subunit 12

1

2

High-throughput

0.479

High

738989

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

738990

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

7

High-throughput

0.479

High

738991

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

1

High-throughput

0.479

High

738992

TAF3
Transcription initiation factor TFIID subunit 3

1

20

High-throughput

0.479

High

738994

ARID2
AT-rich interactive domain-containing protein 2

1

20

High-throughput

0.479

High

738995

LIN54
Protein lin-54 homolog

1

4

High-throughput

0.479

High

738996

TAF2
Transcription initiation factor TFIID subunit 2

1

4

High-throughput

0.479

High

738997

NFRKB
Nuclear factor related to kappa-B-binding protein

1

19

High-throughput

0.479

High

738998

SRCAP
Helicase SRCAP

1

20

High-throughput

0.479

High

738999

ASXL2
Putative Polycomb group protein ASXL2

1

20

High-throughput

0.479

High

739000

KANL1
KAT8 regulatory NSL complex subunit 1

1

2

High-throughput

0.479

High

739001

POGZ
Pogo transposable element with ZNF domain

1

4

High-throughput

0.479

High

739002

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

20

High-throughput

0.479

High

739003

PB1
Protein polybromo-1

1

20

High-throughput

0.479

High

739004

MGAP
MAX gene-associated protein

1

8

High-throughput

0.479

High

739005

ZZZ3
ZZ-type zinc finger-containing protein 3

1

1

High-throughput

0.479

High

739006

ZN687
Zinc finger protein 687

1

4

High-throughput

0.479

High

739007

KDM1B
Lysine-specific histone demethylase 2

1

1

High-throughput

0.479

High

739008

NUP43
Nucleoporin Nup43

1

13

High-throughput

0.479

High

739009

PHF10
PHD finger protein 10

1

20

High-throughput

0.479

High

739010

GATD1
GATA zinc finger domain-containing protein 1

1

4

High-throughput

0.479

High

739012

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

7

High-throughput

0.479

High

739013

KAT2A
Histone acetyltransferase KAT2A

1

20

High-throughput

0.479

High

739014

KAT2B
Histone acetyltransferase KAT2B

1

20

High-throughput

0.479

High

739015

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

12

High-throughput

0.479

High

739016

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

14

High-throughput

0.479

High

739017

SGF29
SAGA-associated factor 29

1

1

High-throughput

0.479

High

739018

MCRS1
Microspherule protein 1

1

4

High-throughput

0.479

High

739019

EP400
E1A-binding protein p400

1

20

High-throughput

0.479

High

739020

PHF12
PHD finger protein 12

1

20

High-throughput

0.479

High

739022

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

14

High-throughput

0.479

High

739023

DDA1
DET1- and DDB1-associated protein 1

1

2

High-throughput

0.479

High

739024

KLF16
Krueppel-like factor 16

1

20

High-throughput

0.479

High

739025

PCGF6
Polycomb group RING finger protein 6

1

20

High-throughput

0.479

High

739026

ARP6
Actin-related protein 6

1

6

High-throughput

0.479

High

739028

ING2
Inhibitor of growth protein 2

1

6

High-throughput

0.479

High

739029

EPC1
Enhancer of polycomb homolog 1

1

3

High-throughput

0.479

High

739030

ZN644
Zinc finger protein 644

1

10

High-throughput

0.479

High

739031

KAT8
Histone acetyltransferase KAT8

1

7

High-throughput

0.479

High

739032

ARP5
Actin-related protein 5

1

10

High-throughput

0.479

High

739033

KANL2
KAT8 regulatory NSL complex subunit 2

1

2

High-throughput

0.479

High

739034

GRPE1
GrpE protein homolog 1, mitochondrial

1

7

High-throughput

0.479

High

739035

BRMS1
Breast cancer metastasis-suppressor 1

1

7

High-throughput

0.479

High

739036

BRD7
Bromodomain-containing protein 7

1

20

High-throughput

0.479

High

739039

CXXC1
CXXC-type zinc finger protein 1

1

20

High-throughput

0.479

High

739040

KANL3
KAT8 regulatory NSL complex subunit 3

1

2

High-throughput

0.479

High

739041

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

14

High-throughput

0.479

High

739042

MO4L1
Mortality factor 4-like protein 1

1

3

High-throughput

0.479

High

739043

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

739044

INO80
Chromatin-remodeling ATPase INO80

1

20

High-throughput

0.479

High

739045

KMT2B
Histone-lysine N-methyltransferase 2B

1

20

High-throughput

0.479

High

739046

ZN148
Zinc finger protein 148

1

12

High-throughput

0.479

High

739049

TRRAP
Transformation/transcription domain-associated protein

1

7

High-throughput

0.479

High

739050

HCFC2
Host cell factor 2

1

5

High-throughput

0.479

High

739051

ZHX2
Zinc fingers and homeoboxes protein 2

1

12

High-throughput

0.479

High

718678

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

1

Small-scale

0.470

High

738955

CD68
Macrosialin

1

1

Small-scale

0.470

High

455707

H10
Histone H1.0

1

0

High-throughput

0.458

High

157004

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.437

High

456094

FES
Tyrosine-protein kinase Fes/Fps

1

5

Small-scale

0.437

High

663845

FCAR
Immunoglobulin alpha Fc receptor

1

2

Small-scale

0.437

High

738976

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

3

High-throughput

0.437

High

738993

ZMYM4
Zinc finger MYM-type protein 4

1

7

High-throughput

0.437

High

739037

RBM28
RNA-binding protein 28

1

2

High-throughput

0.437

High

739048

RM11
Large ribosomal subunit protein uL11m

1

2

High-throughput

0.437

High

738956

BCL6
B-cell lymphoma 6 protein

1

0

Small-scale

0.426

High

416953

CY24B
NADPH oxidase 2

1

0

Small-scale

0.269

Low

378611

IL2RA
Interleukin-2 receptor subunit alpha

1

0

Small-scale

0.249

Low

739027

TOLIP
Toll-interacting protein

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025