HitPredict

Interactor 1: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Interactor 2: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	21996738
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1089 Hs			1 870
+	Hs
		609215 FGFR3_HUMAN (745-969): 1.84e-76: 270: 40.74		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		609615 FGFR3_HUMAN (745-969): 1.84e-76: 270: 40.74		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		572603 VGFR1_HUMAN (18-659): 1.85e-51: 200: 18.22		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		729628 VGFR2_HUMAN (7-588): 8.16e-51: 198: 17.81		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		601480 FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		601616 FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		607921 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		507913 FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		608198 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		508270 FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71		DYN3_HUMAN (1-870): 0: 994: 78.41