HitPredict

Interactor 1: PECA1 (P16284)
Platelet endothelial cell adhesion molecule (PECAM-1) (EndoCAM) (GPIIA') (PECA1) (CD antigen CD31)
Gene: PECAM1

Interactor 2: CSK (P41240)
Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)
Gene: CSK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	9624175
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 738 Hs			1 450
+	Hs
		411985 PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00		FYN_HUMAN (12-442): 1.26e-170: 491: 36.77
+	Hs
		522751 PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00		SRC_HUMAN (12-442): 8.48e-171: 491: 39.33
+	Hs
		433242 PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00		YES_HUMAN (12-442): 5.99e-170: 490: 37.30
+	Hs
		411584 PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00		LCK_HUMAN (5-443): 1.95e-168: 485: 38.55
+	Hs
		557441 PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00		ABL2_HUMAN (4-443): 1.63e-160: 485: 39.33
+	Hs
		442774 PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00		HCK_HUMAN (3-445): 6.38e-167: 481: 36.32
+	Hs
		433561 PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00		LYN_HUMAN (4-445): 3.75e-160: 463: 37.12
+	Hs
		434019 ROBO2_HUMAN (11-737): 1.39e-82: 288: 12.20		LYN_HUMAN (4-445): 3.75e-160: 463: 37.12
+	Hs
		433804 SDK2_HUMAN (247-738): 8.87e-51: 194: 12.69		LYN_HUMAN (4-445): 3.75e-160: 463: 37.12
+	Hs
		297880 NFASC_HUMAN (292-736): 1.17e-37: 153: 12.71		ABL1_HUMAN (5-447): 1.78e-164: 494: 37.83
+	Hs
		297881 NFASC_HUMAN (292-736): 1.17e-37: 153: 12.71		FYN_HUMAN (12-442): 1.26e-170: 491: 36.77
+	Mm
		639452 FCRL5_MOUSE (230-631): 2.04e-45: 173: 17.99		LYN_MOUSE (4-445): 3.96e-160: 463: 36.90
+	Hs
		433569 CD22_HUMAN (282-633): 8.62e-41: 162: 15.93		LYN_HUMAN (4-445): 3.75e-160: 463: 37.12
+	Hs
		434111 ROBO1_HUMAN (405-725): 5.45e-33: 139: 11.87		LYN_HUMAN (4-445): 3.75e-160: 463: 37.12
+	Hs
		433742 PTK7_HUMAN (8-235): 3.28e-27: 120: 12.45		LYN_HUMAN (4-445): 3.75e-160: 463: 37.12
+	Hs
		433249 VCAM1_HUMAN (28-407): 7.14e-17: 86.9: 19.75		YES_HUMAN (12-442): 5.99e-170: 490: 37.30
+	Hs
		255429 OBSL1_HUMAN (72-603): 1.4e-14: 80.3: 15.01		LCK_HUMAN (5-443): 1.95e-168: 485: 38.55