Protein: CCNL2
Cyclin-L2 (Paneth cell-enhanced expression protein)

Gene: CCNL2
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q96S94

Gene Ontology (top 5):
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016538 - cyclin-dependent protein serine/threonine kinase regulator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1402453

CD11A
Cyclin-dependent kinase 11A

4

20

Small-scale

0.895

High

997959

CSK21
Casein kinase II subunit alpha

3

20

Small-scale

0.861

High

625573

CSK22
Casein kinase II subunit alpha'

3

20

High-throughput

0.855

High

1336360

CCNY
Cyclin-Y

3

0

High-throughput

0.816

High

650570

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

3

High-throughput

0.691

High

557440

SRC
Proto-oncogene tyrosine-protein kinase Src

3

4

High-throughput

0.667

High

767310

MERL
Merlin

3

3

High-throughput

0.667

High

1111965

SNX1
Sorting nexin-1

3

2

High-throughput

0.667

High

1239652

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

3

2

Small-scale

0.667

High

1279297

I2BP2
Interferon regulatory factor 2-binding protein 2

3

2

High-throughput

0.667

High

1306951

I2BP1
Interferon regulatory factor 2-binding protein 1

3

1

High-throughput

0.667

High

1145336

RNPS1
RNA-binding protein with serine-rich domain 1

3

4

High-throughput

0.650

High

1115940

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

20

Small-scale

0.647

High

1202492

RUN3A
RUN domain-containing protein 3A

3

0

High-throughput

0.646

High

212856

ZBT43
Zinc finger and BTB domain-containing protein 43

2

2

High-throughput

0.628

High

603343

KPCA
Protein kinase C alpha type

1

3

High-throughput

0.618

High

651706

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

3

High-throughput

0.618

High

897368

CDK7
Cyclin-dependent kinase 7

1

20

High-throughput

0.618

High

440690

FYN
Tyrosine-protein kinase Fyn

2

4

High-throughput

0.611

High

1092346

CSTF3
Cleavage stimulation factor subunit 3

2

1

High-throughput

0.611

High

870971

IREB2
Iron-responsive element-binding protein 2

3

3

High-throughput

0.609

High

1402441

ULBP3
UL16-binding protein 3

3

1

High-throughput

0.609

High

191764

MAGB2
Melanoma-associated antigen B2

2

1

High-throughput

0.606

High

1357729

TRI41
E3 ubiquitin-protein ligase TRIM41

2

3

High-throughput

0.606

High

1402438

MDFI
MyoD family inhibitor

2

1

High-throughput

0.606

High

180168

ZBT7B
Zinc finger and BTB domain-containing protein 7B

2

0

High-throughput

0.580

High

894992

EMD
Emerin

2

0

High-throughput

0.580

High

463205

YES
Tyrosine-protein kinase Yes

2

4

High-throughput

0.558

High

520709

RRAS
Ras-related protein R-Ras

2

1

High-throughput

0.558

High

618481

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

2

2

High-throughput

0.558

High

893522

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

2

2

High-throughput

0.558

High

948375

KR122
Keratin-associated protein 12-2

2

2

High-throughput

0.553

High

1295093

F90A1
Protein FAM90A1

2

1

High-throughput

0.553

High

1402454

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

2

3

High-throughput

0.553

High

1402456

DCAF1
DDB1- and CUL4-associated factor 1

1

5

Small-scale

0.552

High

192956

CLOCK
Circadian locomoter output cycles protein kaput

1

2

High-throughput

0.536

High

848705

MAGA9
Melanoma-associated antigen 9

1

1

High-throughput

0.536

High

911947

JAK3
Tyrosine-protein kinase JAK3

1

5

High-throughput

0.536

High

1110011

HDAC1
Histone deacetylase 1

1

1

High-throughput

0.536

High

1132631

KIF22
Kinesin-like protein KIF22

1

1

High-throughput

0.536

High

1246446

FIGLA
Factor in the germline alpha

1

1

High-throughput

0.536

High

1348839

ZCRB1
Zinc finger CCHC-type and RNA-binding motif-containing protein 1

1

9

High-throughput

0.536

High

1402448

S30BP
SAP30-binding protein

1

1

High-throughput

0.536

High

295403

CBR3
Carbonyl reductase [NADPH] 3

1

0

High-throughput

0.513

High

948577

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

1271987

CENPQ
Centromere protein Q

1

0

High-throughput

0.513

High

1295291

P66A
Transcriptional repressor p66-alpha

1

0

High-throughput

0.513

High

1402440

MND1
Meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.513

High

801480

HSPA9
Stress-70 protein, mitochondrial

1

1

High-throughput

0.489

High

1249835

BTNL9
Butyrophilin-like protein 9

1

4

High-throughput

0.489

High

1290408

LRRT4
Leucine-rich repeat transmembrane neuronal protein 4

1

2

High-throughput

0.489

High

1311839

DHX40
Probable ATP-dependent RNA helicase DHX40

1

2

High-throughput

0.489

High

1369521

KIFA3
Kinesin-associated protein 3

1

6

High-throughput

0.489

High

320758

UBXN7
UBX domain-containing protein 7

1

1

High-throughput

0.479

High

325993

UBR5
E3 ubiquitin-protein ligase UBR5

1

8

High-throughput

0.479

High

463718

LYN
Tyrosine-protein kinase Lyn

1

4

High-throughput

0.479

High

540076

BCR
Breakpoint cluster region protein

1

3

High-throughput

0.479

High

667419

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

5

Small-scale

0.479

High

696281

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

High-throughput

0.479

High

995214

CSK2B
Casein kinase II subunit beta

1

3

High-throughput

0.479

High

1104324

ORC1
Origin recognition complex subunit 1

1

4

Small-scale

0.479

High

1141274

BRD3
Bromodomain-containing protein 3

1

14

High-throughput

0.479

High

1402447

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1402449

XPO7
Exportin-7

1

5

High-throughput

0.479

High

1402451

SNX6
Sorting nexin-6

1

2

High-throughput

0.479

High

1402455

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

1

Small-scale

0.479

High

882833

EFTU
Elongation factor Tu, mitochondrial

1

2

High-throughput

0.470

High

252479

DIAP1
Protein diaphanous homolog 1

1

0

High-throughput

0.458

High

1083298

AP1B1
AP-1 complex subunit beta-1

1

0

High-throughput

0.458

High

1244819

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

1006167

PI42B
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

1

2

High-throughput

0.445

High

1016576

SRSF3
Serine/arginine-rich splicing factor 3

1

16

Small-scale

0.445

High

1029539

SRSF2
Serine/arginine-rich splicing factor 2

1

8

Small-scale

0.445

High

1061108

SRSF1
Serine/arginine-rich splicing factor 1

1

15

Small-scale

0.445

High

1062088

SRSF4
Serine/arginine-rich splicing factor 4

1

12

Small-scale

0.445

High

1099209

SRSF5
Serine/arginine-rich splicing factor 5

1

14

Small-scale

0.445

High

1099488

SRSF6
Serine/arginine-rich splicing factor 6

1

16

Small-scale

0.445

High

1160049

SRSF7
Serine/arginine-rich splicing factor 7

1

15

Small-scale

0.445

High

1349216

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

2

High-throughput

0.445

High

716049

GNA11
Guanine nucleotide-binding protein subunit alpha-11

1

2

High-throughput

0.437

High

1047473

K1C17
Keratin, type I cytoskeletal 17

1

8

High-throughput

0.437

High

1402444

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

2

High-throughput

0.437

High

274225

ANR17
Ankyrin repeat domain-containing protein 17

1

0

High-throughput

0.426

High

1143850

TCAL1
Transcription elongation factor A protein-like 1

1

0

High-throughput

0.426

High

1391100

TRM61
tRNA

1

0

High-throughput

0.426

High

1402450

TRM6
tRNA

1

0

High-throughput

0.426

High

331792

MTMR5
Myotubularin-related protein 5

1

1

High-throughput

0.407

High

607315

NEUM
Neuromodulin

3

0

High-throughput

0.347

High

659054

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

3

0

High-throughput

0.347

High

1088161

CNTN1
Contactin-1

3

0

High-throughput

0.347

High

1346851

OCC1
Overexpressed in colon carcinoma 1 protein

2

0

High-throughput

0.328

High

1359124

PIHD2
PIH1 domain-containing protein 2

2

0

High-throughput

0.316

High

1402446

ABCF2
ATP-binding cassette sub-family F member 2

2

0

High-throughput

0.298

High

1059126

PIGF
GPI ethanolamine phosphate transferase, stabilizing subunit

1

0

High-throughput

0.279

Low

1402443

CB39L
Calcium-binding protein 39-like

1

0

High-throughput

0.279

Low

1402445

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.279

Low

539570

PYGB
Glycogen phosphorylase, brain form

1

0

High-throughput

0.249

Low

1152842

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.249

Low

1257755

VP13C
Intermembrane lipid transfer protein VPS13C

1

0

Small-scale

0.249

Low

1363268

ASM3B
Acid sphingomyelinase-like phosphodiesterase 3b

1

0

High-throughput

0.249

Low

1402442

EHD1
EH domain-containing protein 1

1

0

High-throughput

0.249

Low

1402452

EPCR
Endothelial protein C receptor

1

0

High-throughput

0.249

Low

289807

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.232

Low

1402439

THUM3
tRNA

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025