HitPredict

Interactor 1: IL2RB (P16297)
Interleukin-2 receptor subunit beta (IL-2 receptor subunit beta) (IL-2R subunit beta) (IL-2RB) (High affinity IL-2 receptor subunit beta) (p70-75) (CD antigen CD122)
Gene: IL2RB

Interactor 2: STA5A (P42230)
Signal transducer and activator of transcription 5A (Mammary gland factor)
Gene: Stat5a

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21516110
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019221 - cytokine-mediated signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 539 Mm			1 793
+	Mm
		557513 IL2RB_MOUSE (1-539): 0: 615: 100.00		STA5B_MOUSE (1-773): 0: 1073: 93.57
+	Hs
		540452 IL2RB_HUMAN (1-539): 0: 561: 56.66		STA5A_HUMAN (1-793): 0: 1102: 96.35
+	Hs
		540455 IL2RB_HUMAN (1-539): 0: 561: 56.66		STA5B_HUMAN (1-773): 0: 1060: 91.78
+	Mm
		786650 PRLR_MOUSE (6-413): 2.7e-85: 277: 14.45		STA5A_MOUSE (1-793): 0: 1134: 100.00
+	Hs
		540451 IL2RB_HUMAN (1-539): 0: 561: 56.66		STAT1_HUMAN (1-758): 0: 784: 27.79
+	Hs
		540463 IL2RB_HUMAN (1-539): 0: 561: 56.66		STAT4_HUMAN (1-725): 0: 750: 29.49
+	Hs
		581154 EPOR_HUMAN (1-375): 5.28e-60: 208: 17.57		STA5A_HUMAN (1-793): 0: 1102: 96.35
+	Mm
		562611 GHR_MOUSE (16-289): 5.3e-47: 175: 13.19		STA5A_MOUSE (1-793): 0: 1134: 100.00
+	Hs
		540449 IL2RB_HUMAN (1-539): 0: 561: 56.66		STAT3_HUMAN (1-718): 0: 739: 30.09
+	Hs
		560469 PRLR_HUMAN (24-400): 7.23e-61: 213: 13.57		STA5B_HUMAN (1-773): 0: 1060: 91.78
+	Mm
		562612 GHR_MOUSE (16-289): 5.3e-47: 175: 13.19		STA5B_MOUSE (1-773): 0: 1073: 93.57
+	Hs
		770183 IL6RB_HUMAN (20-350): 7.79e-63: 223: 13.75		STAT1_HUMAN (1-758): 0: 784: 27.79
+	Hs
		770182 IL6RB_HUMAN (20-350): 7.79e-63: 223: 13.75		STAT3_HUMAN (1-718): 0: 739: 30.09
+	Hs
		786348 I13R2_HUMAN (13-262): 1.85e-47: 171: 13.39		STAT1_HUMAN (1-758): 0: 784: 27.79
+	Hs
		776798 CSF3R_HUMAN (2-353): 1.49e-48: 182: 16.62		STAT3_HUMAN (1-718): 0: 739: 30.09
+	Hs
		1059007 I12R2_HUMAN (20-331): 7.7e-43: 165: 16.25		STAT4_HUMAN (1-725): 0: 750: 29.49
+	Mm
		562610 GHR_MOUSE (16-289): 5.3e-47: 175: 13.19		STAT3_MOUSE (1-718): 0: 740: 30.09
+	Mm
		558504 IL4RA_MOUSE (16-321): 2.06e-44: 170: 18.85		STAT3_MOUSE (1-718): 0: 740: 30.09
+	Mm
		558505 IL4RA_MOUSE (16-321): 2.06e-44: 170: 18.85		STAT6_MOUSE (1-757): 0: 739: 38.51
+	Hs
		622729 IL4RA_HUMAN (6-321): 4.26e-43: 166: 17.50		STAT6_HUMAN (1-739): 0: 732: 38.45