HitPredict

Interactor 1: PP2BB (P16298)
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calmodulin-dependent calcineurin A subunit beta isoform) (CNA beta)
Gene: PPP3CB

Interactor 2: PP2BA (Q08209)
Protein phosphatase 3 catalytic subunit alpha (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calcineurin A alpha) (Calmodulin-dependent calcineurin A subunit alpha isoform) (CNA alpha) (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform)
Gene: PPP3CA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Metallophos~Metallophos
Common GO terms GO:0004722 - protein serine/threonine phosphatase activity
GO:0005509 - calcium ion binding
GO:0005516 - calmodulin binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 21 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 524
Hs

1 521
+ Hs
+ Dm
+ Hs
+ Mm
+ Sc
+ Sc
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024