HitPredict

Interactor 1: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Interactor 2: MAP4 (P27816)
Microtubule-associated protein 4 (MAP-4)
Gene: MAP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 Hs			1 1152
+	Hs
		653918 P85A_HUMAN (241-376): 1.37e-22: 101: 19.57		MAP4_HUMAN (1-1152): 1.33e-115: 388: 100.00
+	Hs
		557740 NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00		MINK1_HUMAN (638-935): 1.29e-09: 65: 15.48
+	Hs
		203208 NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00		SYNJ1_HUMAN (481-895): 1.27e-09: 64.9: 9.35
+	Hs
		209112 NCK2_HUMAN (1-376): 7.1e-90: 277: 68.24		MINK1_HUMAN (638-935): 1.29e-09: 65: 15.48
+	Hs
		496365 P85A_HUMAN (241-376): 1.37e-22: 101: 19.57		TAU_HUMAN (367-1125): 2.98e-44: 174: 21.01
+	Hs
		411960 FYN_HUMAN (7-173): 7.47e-21: 96: 15.39		TAU_HUMAN (367-1125): 2.98e-44: 174: 21.01
+	Hs
		522749 SRC_HUMAN (5-114): 1.61e-15: 79.7: 22.32		MUC1_HUMAN (292-1100): 3.81e-45: 180: 16.01
+	Hs
		496189 SRC_HUMAN (5-114): 1.61e-15: 79.7: 22.32		TAU_HUMAN (367-1125): 2.98e-44: 174: 21.01
+	Hs
		496788 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		TAU_HUMAN (367-1125): 2.98e-44: 174: 21.01
+	Hs
		411964 FYN_HUMAN (7-173): 7.47e-21: 96: 15.39		MTAP2_HUMAN (64-1125): 1.27e-31: 136: 15.31
+	Hs
		503258 SRC_HUMAN (5-114): 1.61e-15: 79.7: 22.32		MTAP2_HUMAN (64-1125): 1.27e-31: 136: 15.31
+	Hs
		503278 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		MTAP2_HUMAN (64-1125): 1.27e-31: 136: 15.31
+	Hs
		64077 SRC_HUMAN (5-114): 1.61e-15: 79.7: 22.32		L37A2_HUMAN (199-978): 3.81e-29: 128: 10.47
+	Rn
		192744 SRBS2_RAT (3-162): 4.86e-25: 109: 28.05		SYNJ1_RAT (222-755): 4.3e-09: 63.4: 9.47
+	Hs
		203192 SRBS2_HUMAN (64-287): 1.79e-23: 104: 18.26		SYNJ1_HUMAN (481-895): 1.27e-09: 64.9: 9.35
+	Hs
		412362 FYN_HUMAN (7-173): 7.47e-21: 96: 15.39		MAGE1_HUMAN (576-960): 5.19e-09: 62.7: 18.34
+	Hs
		203230 SH319_HUMAN (8-254): 6.26e-19: 90.5: 19.84		SYNJ1_HUMAN (481-895): 1.27e-09: 64.9: 9.35
+	Hs
		203228 ITSN1_HUMAN (5-286): 1.55e-16: 83.6: 17.07		SYNJ1_HUMAN (481-895): 1.27e-09: 64.9: 9.35
+	Mm
		1112482 GRB2_MOUSE (1-61): 1.55e-16: 79.4: 29.03		GARE1_MOUSE (608-918): 1.05e-09: 65: 18.77
+	Hs
		203218 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		SYNJ1_HUMAN (481-895): 1.27e-09: 64.9: 9.35