Protein: TTC27
Tetratricopeptide repeat protein 27 (TPR repeat protein 27)

Gene: TTC27
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q6P3X3

Gene Ontology (top 5):

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

289583

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

2

4

High-throughput

0.705

High

1138322

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

5

4

High-throughput

0.650

High

372327

MYC
Myc proto-oncogene protein

2

4

High-throughput

0.558

High

1242066

TTC27
Tetratricopeptide repeat protein 27

1

18

High-throughput

0.553

High

1209288

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

6

High-throughput

0.549

High

50587

HACL2
2-hydroxyacyl-CoA lyase 2

2

1

High-throughput

0.549

High

1232081

VASN
Vasorin

1

2

High-throughput

0.514

High

1154106

ITSN1
Intersectin-1

1

2

High-throughput

0.494

High

920463

DAPK1
Death-associated protein kinase 1

1

9

High-throughput

0.489

High

1242110

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

7

High-throughput

0.489

High

182598

GP182
G-protein coupled receptor 182

1

5

High-throughput

0.489

High

351911

S1PR4
Sphingosine 1-phosphate receptor 4

1

3

High-throughput

0.489

High

634767

GRAH
Granzyme H

1

5

High-throughput

0.489

High

1131670

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

3

High-throughput

0.489

High

1142085

P2RY6
P2Y purinoceptor 6

1

6

High-throughput

0.489

High

1242073

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

5

High-throughput

0.489

High

1242084

HDA11
Histone deacetylase 11

1

9

High-throughput

0.489

High

1242088

OPALI
Opalin

1

1

High-throughput

0.489

High

1242092

KLK15
Kallikrein-15

1

6

High-throughput

0.489

High

1242103

ZNHI2
Zinc finger HIT domain-containing protein 2

1

1

High-throughput

0.489

High

1242104

DJC12
DnaJ homolog subfamily C member 12

1

9

High-throughput

0.489

High

1242106

RUVB2
RuvB-like 2

1

3

High-throughput

0.489

High

1242107

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

1

High-throughput

0.489

High

1242109

KLK5
Kallikrein-5

1

5

High-throughput

0.489

High

277367

TP4A3
Protein tyrosine phosphatase type IVA 3

1

2

High-throughput

0.470

High

384453

CRYAA
Alpha-crystallin A chain

1

4

High-throughput

0.457

High

174532

TRI66
Tripartite motif-containing protein 66

1

10

High-throughput

0.437

High

246690

KDM1A
Lysine-specific histone demethylase 1A

1

5

High-throughput

0.437

High

293866

CD123
Translation initiation factor eIF2 assembly protein

1

3

High-throughput

0.437

High

363433

EGFR
Epidermal growth factor receptor

1

4

High-throughput

0.437

High

412107

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.437

High

447123

NPM
Nucleophosmin

1

1

High-throughput

0.437

High

588950

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.437

High

610721

TCPA
T-complex protein 1 subunit alpha

1

7

High-throughput

0.437

High

768455

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

821414

TCPZ
T-complex protein 1 subunit zeta

1

7

High-throughput

0.437

High

830934

CCNF
Cyclin-F

1

9

High-throughput

0.437

High

876024

TCPE
T-complex protein 1 subunit epsilon

1

10

High-throughput

0.437

High

876899

KC1A
Casein kinase I isoform alpha

1

4

High-throughput

0.437

High

879196

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

5

High-throughput

0.437

High

881985

TCPG
T-complex protein 1 subunit gamma

1

10

High-throughput

0.437

High

899441

TCPD
T-complex protein 1 subunit delta

1

8

High-throughput

0.437

High

941467

CTBP2
C-terminal-binding protein 2

1

5

High-throughput

0.437

High

1007085

TCPB
T-complex protein 1 subunit beta

1

9

High-throughput

0.437

High

1109825

HDAC1
Histone deacetylase 1

1

8

High-throughput

0.437

High

1113423

CUL3
Cullin-3

1

8

High-throughput

0.437

High

1121252

TRI14
Tripartite motif-containing protein 14

1

5

High-throughput

0.437

High

1152431

T22D1
TSC22 domain family protein 1

1

16

High-throughput

0.437

High

1178204

CL16A
Protein CLEC16A

1

2

High-throughput

0.437

High

1242068

LMBRL
Protein LMBR1L

1

4

High-throughput

0.437

High

1242070

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.437

High

1242071

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.437

High

1242076

ASXL1
Polycomb group protein ASXL1

1

6

High-throughput

0.437

High

1242079

ASB11
Ankyrin repeat and SOCS box protein 11

1

6

High-throughput

0.437

High

1242080

CSN5
COP9 signalosome complex subunit 5

1

5

High-throughput

0.437

High

1242081

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

3

High-throughput

0.437

High

1242082

PF21A
PHD finger protein 21A

1

8

High-throughput

0.437

High

1242083

FAF2
FAS-associated factor 2

1

1

High-throughput

0.437

High

1242087

CI072
Guanine nucleotide exchange factor C9orf72

1

4

High-throughput

0.437

High

1242089

TCPH
T-complex protein 1 subunit eta

1

10

High-throughput

0.437

High

1242093

PKHA4
Pleckstrin homology domain-containing family A member 4

1

14

High-throughput

0.437

High

1242094

EGLN3
Prolyl hydroxylase EGLN3

1

4

High-throughput

0.437

High

1242095

BRF2
Transcription factor IIIB 50 kDa subunit

1

3

High-throughput

0.437

High

1242096

SENP2
Sentrin-specific protease 2

1

1

Small-scale

0.437

High

1242097

FBX6
F-box only protein 6

1

5

High-throughput

0.437

High

1242099

FXL12
F-box/LRR-repeat protein 12

1

3

Small-scale

0.437

High

1242102

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.437

High

166326

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

4

High-throughput

0.407

High

380072

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

2

High-throughput

0.407

High

1101535

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

5

High-throughput

0.407

High

1209922

PPM1L
Protein phosphatase 1L

1

3

High-throughput

0.407

High

1226888

A16L1
Autophagy-related protein 16-1

1

13

High-throughput

0.407

High

1240871

S27A4
Long-chain fatty acid transport protein 4

1

5

High-throughput

0.407

High

1242067

S27A1
Long-chain fatty acid transport protein 1

1

5

High-throughput

0.407

High

1242075

SPNS2
Sphingosine-1-phosphate transporter SPNS2

1

2

High-throughput

0.407

High

1242090

S39A3
Zinc transporter ZIP3

1

2

High-throughput

0.407

High

1242098

S22AB
Solute carrier family 22 member 11

1

5

High-throughput

0.407

High

1242105

XCT
Cystine/glutamate transporter

1

3

High-throughput

0.407

High

1241654

PRP8
Pre-mRNA-processing-splicing factor 8

3

0

High-throughput

0.342

High

1242108

AAR2
Protein AAR2 homolog

3

0

High-throughput

0.342

High

351121

ECD
Protein ecdysoneless homolog

2

0

High-throughput

0.318

High

1242101

NCDN
Neurochondrin

2

0

High-throughput

0.318

High

139239

UPK2
Uroplakin-2

2

0

High-throughput

0.313

High

144443

SCD
Stearoyl-CoA desaturase

1

0

High-throughput

0.279

Low

563924

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.279

Low

733005

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

0

High-throughput

0.279

Low

1201267

EAPP
E2F-associated phosphoprotein

1

0

High-throughput

0.279

Low

1242074

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.279

Low

1242077

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

1242078

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1242085

DTBP1
Dysbindin

1

0

High-throughput

0.279

Low

1242091

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

1242100

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.279

Low

1242111

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.279

Low

1242113

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

1

0

High-throughput

0.279

Low

1242112

PHLA3
Pleckstrin homology-like domain family A member 3

1

0

High-throughput

0.269

Low

1229531

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1242069

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.249

Low

1242086

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1157175

S15A2
Solute carrier family 15 member 2

1

0

High-throughput

0.232

Low

1211916

S35F1
Solute carrier family 35 member F1

1

0

High-throughput

0.232

Low

1242072

RIC3
Protein RIC-3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025