HitPredict

Interactor 1: GROU (P16371)
Protein groucho (Enhancer of split m9/10 protein) (E(spl)m9/10)
Gene: gro

Interactor 2: UBX (P83949)
Homeotic protein ultrabithorax
Gene: UBX

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	30247122
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005667 - transcription regulator complex GO:0006355 - regulation of DNA-templated transcription GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 730 Dm			1 389
+	Hs
		882123 TLE4_HUMAN (1-730): 4.44e-156: 473: 60.87		GSC_HUMAN (137-378): 1.64e-36: 135: 19.59
+	Hs
		882121 TLE1_HUMAN (1-730): 6.59e-154: 467: 60.08		GSC_HUMAN (137-378): 1.64e-36: 135: 19.59
+	Hs
		980644 TLE1_HUMAN (1-730): 6.59e-154: 467: 60.08		BARH1_HUMAN (123-377): 6.27e-34: 130: 19.16
+	Hs
		211840 TLE4_HUMAN (1-730): 4.44e-156: 473: 60.87		TLX3_HUMAN (118-388): 1.09e-31: 123: 17.34
+	Hs
		211837 TLE1_HUMAN (1-730): 6.59e-154: 467: 60.08		TLX3_HUMAN (118-388): 1.09e-31: 123: 17.34
+	Hs
		980663 TLE1_HUMAN (1-730): 6.59e-154: 467: 60.08		HESX1_HUMAN (192-358): 1.1e-32: 123: 21.77
+	Hs
		882122 TLE3_HUMAN (1-730): 2.82e-146: 447: 57.27		GSC_HUMAN (137-378): 1.64e-36: 135: 19.59
+	Hs
		211839 TLE3_HUMAN (1-730): 2.82e-146: 447: 57.27		TLX3_HUMAN (118-388): 1.09e-31: 123: 17.34
+	Hs
		678903 TLE3_HUMAN (1-730): 2.82e-146: 447: 57.27		HXC8_HUMAN (146-363): 3.56e-32: 123: 31.65
+	Hs
		980675 TLE2_HUMAN (1-730): 8.83e-141: 432: 55.91		EMX2_HUMAN (149-371): 8.54e-35: 130: 21.43
+	Hs
		980714 TLE2_HUMAN (1-730): 8.83e-141: 432: 55.91		BARH1_HUMAN (123-377): 6.27e-34: 130: 19.16
+	Hs
		211838 TLE2_HUMAN (1-730): 8.83e-141: 432: 55.91		TLX3_HUMAN (118-388): 1.09e-31: 123: 17.34
+	Ce
		137685 UNC37_CAEEL (20-730): 1.93e-92: 302: 35.38		HM30_CAEEL (252-378): 2.24e-34: 129: 27.56
+	Ce
		137665 UNC37_CAEEL (20-730): 1.93e-92: 302: 35.38		UNC4_CAEEL (242-378): 3.18e-31: 121: 24.29
+	Ce
		137669 UNC37_CAEEL (20-730): 1.93e-92: 302: 35.38		HM09_CAEEL (232-362): 1.45e-31: 118: 29.77
+	Hs
		447242 TLE5_HUMAN (1-197): 8.88e-84: 265: 49.51		HXB5_HUMAN (193-367): 3.02e-37: 137: 36.00
+	Hs
		882124 TLE5_HUMAN (1-197): 8.88e-84: 265: 49.51		GSC_HUMAN (137-378): 1.64e-36: 135: 19.59
+	Hs
		837946 TLE5_HUMAN (1-197): 8.88e-84: 265: 49.51		MEOX2_HUMAN (114-366): 8.49e-34: 129: 20.16
+	Hs
		211844 TLE5_HUMAN (1-197): 8.88e-84: 265: 49.51		TLX3_HUMAN (118-388): 1.09e-31: 123: 17.34
+	Hs
		678908 TLE5_HUMAN (1-197): 8.88e-84: 265: 49.51		HXC8_HUMAN (146-363): 3.56e-32: 123: 31.65