HitPredict

Interactor 1: TSHR (P16473)
Thyrotropin receptor (Thyroid-stimulating hormone receptor) (TSH-R)
Gene: TSHR

Interactor 2: TBA4A (P68366)
Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain)
Gene: TUBA4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 764 Hs			1 448
+	Hs
		560525 TSHR_HUMAN (1-764): 1.67e-124: 392: 98.30		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		428004 TSHR_HUMAN (1-764): 1.67e-124: 392: 98.30		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		781101 OPRX_HUMAN (420-708): 1.44e-60: 210: 19.54		TBA1C_HUMAN (1-448): 0: 726: 96.21
+	Hs
		781052 OPRX_HUMAN (420-708): 1.44e-60: 210: 19.54		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		1174997 P2RY8_HUMAN (417-739): 1.49e-63: 218: 21.68		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		933794 MTR1L_HUMAN (396-697): 2.69e-67: 235: 19.81		TBB4B_HUMAN (1-437): 0: 695: 40.28
+	Hs
		427968 ADRB2_HUMAN (393-721): 1.48e-63: 219: 17.52		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		428086 MTR1A_HUMAN (417-700): 3.23e-63: 217: 20.60		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		933338 LGR4_HUMAN (223-392): 7.61e-18: 90.5: 13.79		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		1161215 LGR4_HUMAN (223-392): 7.61e-18: 90.5: 13.79		TBA3E_HUMAN (1-439): 0: 698: 94.08
+	Hs
		428406 LGR4_HUMAN (223-392): 7.61e-18: 90.5: 13.79		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		1315161 LGR4_HUMAN (223-392): 7.61e-18: 90.5: 13.79		TBA8_HUMAN (1-440): 0: 691: 90.23