HitPredict

Interactor 1: BIP (P16474)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein homolog) (GRP-78) (Immunoglobulin heavy chain-binding protein homolog) (BiP)
Gene: KAR2

Interactor 2: PWP1 (P21304)
Periodic tryptophan protein 1
Gene: PWP1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	19536198, 16429126
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 682 Sc			1 576
+	Hs
		714020 HS71L_HUMAN (46-666): 0: 920: 61.60		POC1A_HUMAN (224-505): 4.58e-45: 166: 15.19
+	Hs
		504412 HSP7C_HUMAN (48-656): 0: 915: 64.27		POC1A_HUMAN (224-505): 4.58e-45: 166: 15.19
+	Hs
		564125 HSP76_HUMAN (49-673): 0: 911: 59.30		POC1A_HUMAN (224-505): 4.58e-45: 166: 15.19
+	Hs
		503817 HSP7C_HUMAN (48-656): 0: 915: 64.27		WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07
+	Hs
		714094 HS71L_HUMAN (46-666): 0: 920: 61.60		FZR1_HUMAN (337-559): 3.4e-22: 102: 16.96
+	Hs
		504948 HSP7C_HUMAN (48-656): 0: 915: 64.27		FZR1_HUMAN (337-559): 3.4e-22: 102: 16.96
+	Mm
		926171 HSP7C_MOUSE (48-656): 0: 915: 64.27		FZR1_MOUSE (337-559): 1.97e-22: 102: 16.96
+	Hs
		564207 HSP76_HUMAN (49-673): 0: 911: 59.30		FZR1_HUMAN (337-559): 3.4e-22: 102: 16.96
+	Sc
		560644 BIP_YEAST (1-682): 0: 899: 100.00		TAF5_YEAST (376-558): 3.79e-25: 112: 10.50
+	Hs
		871827 HSP72_HUMAN (46-655): 0: 908: 62.34		FZR1_HUMAN (337-559): 3.4e-22: 102: 16.96
+	Hs
		504455 HSP7C_HUMAN (48-656): 0: 915: 64.27		UTP15_HUMAN (283-503): 3.98e-15: 80.4: 22.62
+	Ce
		450531 HSP1_CAEEL (48-656): 0: 901: 62.70		LIN53_CAEEL (330-523): 1.2e-19: 93.4: 16.10
+	Hs
		504344 HSP7C_HUMAN (48-656): 0: 915: 64.27		WDR5B_HUMAN (431-560): 1.02e-11: 68.2: 5.30
+	Hs
		503614 HSP7C_HUMAN (48-656): 0: 915: 64.27		LIS1_HUMAN (468-561): 5.16e-11: 66.7: 10.42
+	Hs
		501913 BIP_HUMAN (44-672): 0: 795: 67.51		WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07
+	Mm
		588745 BIP_MOUSE (44-670): 0: 797: 67.82		FZR1_MOUSE (337-559): 1.97e-22: 102: 16.96
+	Hs
		502675 BIP_HUMAN (44-672): 0: 795: 67.51		FZR1_HUMAN (337-559): 3.4e-22: 102: 16.96
+	Hs
		502072 BIP_HUMAN (44-672): 0: 795: 67.51		PWP1_HUMAN (331-554): 4.52e-20: 95.6: 9.49
+	Ce
		647809 HSP7C_CAEEL (49-672): 0: 781: 66.56		LIN53_CAEEL (330-523): 1.2e-19: 93.4: 16.10
+	Ce
		589754 BIBH_CAEEL (47-672): 0: 765: 65.29		LIN53_CAEEL (330-523): 1.2e-19: 93.4: 16.10