Interactor 1: HEM1 (P13196)
5-aminolevulinate synthase, non-specific, mitochondrial (ALAS-H) (EC 2.3.1.37) (5-aminolevulinic acid synthase 1) (Delta-ALA synthase 1) (Delta-aminolevulinate synthase 1)
Gene: ALAS1

Interactor 2: HSC20 (Q8IWL3)
Iron-sulfur cluster co-chaperone protein HscB (DnaJ homolog subfamily C member 20) [Cleaved into: Iron-sulfur cluster co-chaperone protein HscB, cytoplasmic (C-HSC20); Iron-sulfur cluster co-chaperone protein HscB, mitochondrial]
Gene: HSCB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.571

The method score is based on:

Property Details
Experiments 33957083, 28380382
Identification Methods proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 640
Hs

1 235
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025