Protein: KBL
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (AKB ligase) (EC 2.3.1.29) (Aminoacetone synthase) (Glycine acetyltransferase)

Gene: KBL, GCAT
Organism: Homo sapiens
Interactions: 64
UniProt ID: O75600

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006520 - amino acid metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

278590

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

3

1

High-throughput

0.667

High

288227

LONM
Lon protease homolog, mitochondrial

3

6

High-throughput

0.667

High

288251

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

3

2

High-throughput

0.667

High

288232

CUL3
Cullin-3

2

4

High-throughput

0.611

High

288237

EMB
Embigin

3

2

High-throughput

0.609

High

288234

KPCD1
Serine/threonine-protein kinase D1

2

4

High-throughput

0.571

High

166593

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

3

High-throughput

0.536

High

288212

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

1

High-throughput

0.536

High

288213

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

1

High-throughput

0.536

High

288218

CH60
60 kDa heat shock protein, mitochondrial

1

6

High-throughput

0.536

High

288219

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

3

High-throughput

0.536

High

288222

CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial

1

1

High-throughput

0.536

High

288226

CPSM
Carbamoyl-phosphate synthase [ammonia], mitochondrial

1

3

High-throughput

0.536

High

288228

CACP
Carnitine O-acetyltransferase

1

1

High-throughput

0.536

High

288238

SYDM
Aspartate--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

288239

SPSB3
SPRY domain-containing SOCS box protein 3

1

4

High-throughput

0.536

High

288241

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

3

High-throughput

0.536

High

288247

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

1

1

High-throughput

0.536

High

288250

IMP1L
Mitochondrial inner membrane protease subunit 1

1

3

High-throughput

0.536

High

288253

IMP2L
Mitochondrial inner membrane protease subunit 2

1

3

High-throughput

0.536

High

288256

SYTM
Threonine--tRNA ligase, mitochondrial

1

2

High-throughput

0.536

High

288260

RSAD1
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial

1

1

High-throughput

0.536

High

288261

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

1

High-throughput

0.536

High

288268

DD19B
ATP-dependent RNA helicase DDX19B

1

1

High-throughput

0.536

High

288224

TEAD1
Transcriptional enhancer factor TEF-1

1

0

High-throughput

0.518

High

288230

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

High-throughput

0.518

High

288231

CP24A
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

1

0

High-throughput

0.513

High

288233

SYLM
Leucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

288252

CK5P1
Mitochondrial tRNA methylthiotransferase CDK5RAP1

1

0

High-throughput

0.513

High

288254

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.513

High

288255

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.513

High

288267

SARDH
Sarcosine dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

288217

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

High-throughput

0.501

High

288214

ICAM1
Intercellular adhesion molecule 1

1

2

High-throughput

0.489

High

288223

TNR6
Tumor necrosis factor receptor superfamily member 6

1

1

High-throughput

0.489

High

288225

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

240295

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

288210

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

1

High-throughput

0.479

High

288211

BRD1
Bromodomain-containing protein 1

1

3

High-throughput

0.479

High

288221

SP100
Nuclear autoantigen Sp-100

1

4

High-throughput

0.479

High

288249

CI072
Guanine nucleotide exchange factor C9orf72

1

3

High-throughput

0.479

High

288259

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

288262

BRD7
Bromodomain-containing protein 7

1

3

High-throughput

0.479

High

288265

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

279245

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

288216

NFIC
Nuclear factor 1 C-type

1

0

High-throughput

0.458

High

288229

ATX3
Ataxin-3

1

0

Small-scale

0.458

High

288242

NIN
Ninein

1

0

High-throughput

0.458

High

288215

TBB5
Tubulin beta chain

1

1

High-throughput

0.445

High

288236

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.445

High

288235

CL16A
Protein CLEC16A

1

3

High-throughput

0.437

High

288240

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

288257

TOLIP
Toll-interacting protein

1

1

High-throughput

0.437

High

288258

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

288263

FBX6
F-box only protein 6

1

1

High-throughput

0.437

High

258682

DNJA2
DnaJ homolog subfamily A member 2

1

1

High-throughput

0.407

High

288220

FPR1
fMet-Leu-Phe receptor

1

2

High-throughput

0.407

High

288244

MOT11
Monocarboxylate transporter 11

1

3

High-throughput

0.407

High

288264

CAH10
Carbonic anhydrase-related protein 10

1

1

High-throughput

0.407

High

288245

TM263
Transmembrane protein 263

1

0

High-throughput

0.279

Low

288266

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.279

Low

288248

FAF2
FAS-associated factor 2

1

0

High-throughput

0.249

Low

288243

SPX3
Sugar phosphate exchanger 3

1

0

High-throughput

0.232

Low

288246

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025