HitPredict

Interactor 1: EF3A (P16521)
Elongation factor 3A (EF-3) (EF-3A) (EC 3.6.4.-) (Eukaryotic elongation factor 3) (eEF3) (Translation elongation factor 3A) (Yeast elongation factor 3)
Gene: YEF3

Interactor 2: SSB2 (P40150)
Ribosome-associated molecular chaperone SSB2 (EC 3.6.4.10) (Heat shock protein SSB2) (Hsp70 chaperone Ssb)
Gene: SSB2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	23332755, 19536198
Identification Methods	biochemical, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0010494 - cytoplasmic stress granule GO:0016887 - ATP hydrolysis activity
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1044 Sc			1 613
+	Sc
		510156 EF3A_YEAST (1-1044): 0: 640: 100.00		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		512313 EF3B_YEAST (1-1044): 0: 635: 83.81		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		769709 NEW1_YEAST (11-1039): 9.7e-141: 454: 33.40		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		513063 NEW1_YEAST (11-1039): 9.7e-141: 454: 33.40		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		707866 GCN1_YEAST (5-465): 9.92e-73: 267: 19.83		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		510792 GCN1_YEAST (5-465): 9.92e-73: 267: 19.83		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		767052 ARB1_YEAST (766-1041): 7.09e-31: 131: 14.95		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		511454 ARB1_YEAST (766-1041): 7.09e-31: 131: 14.95		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		768724 GCN20_YEAST (631-1027): 1.84e-27: 121: 19.21		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		511729 GCN20_YEAST (631-1027): 1.84e-27: 121: 19.21		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Hs
		504833 ABCF3_HUMAN (764-1041): 3.54e-30: 130: 13.61		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Sc
		449999 GCN1_YEAST (5-465): 9.92e-73: 267: 19.83		HSP73_YEAST (9-611): 0: 677: 60.66