Interactor 1: PFKA1 (P16861)
ATP-dependent 6-phosphofructokinase subunit alpha (EC 2.7.1.11) (ATP-dependent 6-phosphofructokinase) (ATP-PFK) (Phosphofructokinase 1) (Phosphohexokinase)
Gene: PFK1

Interactor 2: PFKA2 (P16862)
ATP-dependent 6-phosphofructokinase subunit beta (EC 2.7.1.11) (ATP-dependent 6-phosphofructokinase) (ATP-PFK) (Phosphofructokinase 2) (Phosphohexokinase)
Gene: PFK2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 11805826, 11283351, 11805837, 16554755, 18313953, 18719252, 37968396, 20826334, 16429126, unassigned1933, 12051897
Identification Methods tandem affinity purification, two hybrid pooling approach, anti tag coimmunoprecipitation, affinity chromatography technology, protein complementation assay, two hybrid, dihydrofolate reductase reconstruction, electron microscopy
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PFK~PFK, PFK~Pfk_N
Common GO terms GO:0003872 - 6-phosphofructokinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
and 11 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 987
Sc

1 959
+ Sc
+ Sc
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ At
+ At
+ Sa
+ Hs
+ Hs

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Last updated: 15 Jul 2024