HitPredict

Interactor 1: IL7RA (P16871)
Interleukin-7 receptor subunit alpha (IL-7 receptor subunit alpha) (IL-7R subunit alpha) (IL-7R-alpha) (IL-7RA) (CDw127) (CD antigen CD127)
Gene: IL7R

Interactor 2: CISH (Q9NSE2)
Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Protein G18) (Suppressor of cytokine signaling) (SOCS)
Gene: CISH

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	27596538, 27423467
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH2~fn3
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 459 Hs			1 258
+	Hs
		146591 IL7RA_HUMAN (1-459): 0: 877: 100.00		SOCS2_HUMAN (45-258): 1.84e-53: 173: 37.85
+	Hs
		411991 IL7RA_HUMAN (1-459): 0: 877: 100.00		FYN_HUMAN (39-248): 8.37e-42: 151: 13.06
+	Hs
		181790 IL7RA_HUMAN (1-459): 0: 877: 100.00		SOCS1_HUMAN (55-258): 2e-42: 145: 28.16
+	Hs
		562513 IL7RA_HUMAN (1-459): 0: 877: 100.00		P85A_HUMAN (52-188): 2.6e-21: 94.5: 16.06