HitPredict

Interactor 1: YBOX3 (P16989)
Y-box-binding protein 3 (Cold shock domain-containing protein A) (DNA-binding protein A) (Single-strand DNA-binding protein NF-GMB)
Gene: YBX3

Interactor 2: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20020773
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CSD~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0005634 - nucleus GO:0010468 - regulation of gene expression GO:0070935 - 3'-UTR-mediated mRNA stabilization
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 414
+	Hs
		931128 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00
+	Hs
		162160 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		HNRDL_HUMAN (62-376): 5.62e-71: 231: 23.60
+	Hs
		474028 LN28B_HUMAN (63-314): 9.71e-58: 190: 22.39		PAB4L_HUMAN (2-276): 8.18e-56: 189: 16.96
+	Hs
		516350 YBOX3_HUMAN (1-372): 8.1e-79: 248: 100.00		PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95
+	Hs
		852175 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		ROA3_HUMAN (98-269): 2.33e-69: 225: 28.57
+	Hs
		474013 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		PAB4L_HUMAN (2-276): 8.18e-56: 189: 16.96
+	Hs
		474045 YBOX2_HUMAN (58-366): 4.54e-50: 173: 42.54		PAB4L_HUMAN (2-276): 8.18e-56: 189: 16.96
+	Hs
		201712 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		MSI1H_HUMAN (96-409): 4.25e-61: 203: 23.93
+	Hs
		474037 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		PAB4L_HUMAN (2-276): 8.18e-56: 189: 16.96
+	Hs
		931135 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		PABP4_HUMAN (98-274): 3.77e-37: 144: 19.02
+	Hs
		516455 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95
+	Hs
		931406 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		PABP3_HUMAN (2-382): 7.84e-31: 126: 16.41
+	Hs
		1031465 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		PABP4_HUMAN (98-274): 3.77e-37: 144: 19.02
+	Mm
		1225251 LN28A_MOUSE (64-256): 6.42e-42: 147: 27.09		Q99LF8_MOUSE (98-274): 3.98e-36: 141: 18.48
+	Hs
		516697 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95
+	Hs
		931151 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		HNRPD_HUMAN (81-238): 5.59e-21: 95.1: 35.93
+	Mm
		665764 LN28A_MOUSE (64-256): 6.42e-42: 147: 27.09		PABP1_MOUSE (2-382): 8.56e-31: 126: 15.95
+	Hs
		1048233 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		HNRPD_HUMAN (81-238): 5.59e-21: 95.1: 35.93
+	Hs
		1288219 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		MSI2H_HUMAN (41-207): 5.16e-20: 92.2: 23.81