HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: HNRH2 (P55795)
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]
Gene: HNRNPH2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	31324722
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 449
+	Hs
		563460 CFTR_HUMAN (1-1480): 0: 1106: 100.00		HNRPF_HUMAN (1-434): 1.39e-86: 272: 71.95
+	Hs
		550101 CFTR_HUMAN (1-1480): 0: 1106: 100.00		PABP1_HUMAN (1-448): 6.59e-81: 264: 12.71
+	Hs
		563717 CFTR_HUMAN (1-1480): 0: 1106: 100.00		PABP4_HUMAN (1-447): 8.2e-81: 264: 13.35
+	Hs
		564358 CFTR_HUMAN (1-1480): 0: 1106: 100.00		PABP3_HUMAN (1-446): 3.71e-77: 254: 11.99
+	Hs
		563856 CFTR_HUMAN (1-1480): 0: 1106: 100.00		PAP1L_HUMAN (1-446): 3.94e-76: 251: 13.92
+	Hs
		563286 CFTR_HUMAN (1-1480): 0: 1106: 100.00		HNRH1_HUMAN (1-449): 3.2e-73: 239: 96.21
+	Hs
		563285 CFTR_HUMAN (1-1480): 0: 1106: 100.00		HNRH3_HUMAN (10-86): 8.68e-10: 62.2: 33.77
+	Hs
		563164 CFTR_HUMAN (1-1480): 0: 1106: 100.00		NUCL_HUMAN (4-404): 6.64e-09: 60.2: 18.16
+	Sc
		403515 YCFI_YEAST (748-1433): 4.61e-56: 216: 14.59		PABP_YEAST (103-370): 4.42e-34: 136: 13.87
+	Hs
		620524 MRP9_HUMAN (126-648): 4.19e-56: 217: 13.59		NUCL_HUMAN (4-404): 6.64e-09: 60.2: 18.16