HitPredict

Interactor 1: HSP76 (P17066)
Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6)
Gene: HSPA6

Interactor 2: ILK (Q13418)
Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (Beta-integrin-linked kinase) (ILK-1) (ILK-2) (p59ILK)
Gene: ILK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 643 Hs			1 452
+	Hs
		713958 HS71L_HUMAN (1-643): 0: 960: 79.32		ILK_HUMAN (1-452): 1.6e-146: 427: 100.00
+	Hs
		504026 HSP7C_HUMAN (4-615): 0: 940: 79.25		ILK_HUMAN (1-452): 1.6e-146: 427: 100.00
+	Mm
		223283 HSP7C_MOUSE (4-615): 0: 939: 79.25		ILK_MOUSE (1-452): 6.16e-146: 425: 99.56
+	Hs
		871556 HSP72_HUMAN (3-643): 0: 925: 77.45		ILK_HUMAN (1-452): 1.6e-146: 427: 100.00
+	Hs
		411586 HSP76_HUMAN (1-643): 0: 970: 100.00		LCK_HUMAN (167-449): 1.86e-109: 334: 21.99
+	Hs
		411570 HSP7C_HUMAN (4-615): 0: 940: 79.25		LCK_HUMAN (167-449): 1.86e-109: 334: 21.99
+	Hs
		503340 HSP7C_HUMAN (4-615): 0: 940: 79.25		SRC_HUMAN (173-448): 1.71e-98: 307: 24.56
+	Hs
		433227 HSP7C_HUMAN (4-615): 0: 940: 79.25		YES_HUMAN (176-448): 5.77e-98: 305: 26.60