HitPredict

Interactor 1: HSP76 (P17066)
Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6)
Gene: HSPA6

Interactor 2: DNJC7 (Q99615)
DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2)
Gene: DNAJC7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~HSP70
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031072 - heat shock protein binding GO:0051085 - chaperone cofactor-dependent protein refolding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 643 Hs			1 494
+	Hs
		1120567 Q53FA3_HUMAN (1-643): 0: 961: 79.01		DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00
+	Hs
		714055 HS71L_HUMAN (1-643): 0: 960: 79.32		DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00
+	Hs
		564017 HSP76_HUMAN (1-643): 0: 970: 100.00		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		713956 HS71L_HUMAN (1-643): 0: 960: 79.32		DNJC3_HUMAN (14-289): 8.21e-26: 112: 17.83
+	Hs
		174578 HSP7C_HUMAN (4-615): 0: 940: 79.25		OGT1_HUMAN (3-401): 1.62e-31: 130: 13.59
+	Hs
		684439 HS71L_HUMAN (1-643): 0: 960: 79.32		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		279274 HSP76_HUMAN (1-643): 0: 970: 100.00		DNJB5_HUMAN (380-491): 5.82e-19: 90.1: 43.31
+	Hs
		564203 HSP76_HUMAN (1-643): 0: 970: 100.00		DNJB4_HUMAN (380-479): 7.53e-18: 86.7: 45.22
+	Hs
		279280 HS71L_HUMAN (1-643): 0: 960: 79.32		DNJB5_HUMAN (380-491): 5.82e-19: 90.1: 43.31
+	Hs
		564137 HSP76_HUMAN (1-643): 0: 970: 100.00		DNJB3_HUMAN (381-485): 1.24e-16: 78.6: 40.68
+	Hs
		564130 HSP76_HUMAN (1-643): 0: 970: 100.00		DNJB8_HUMAN (381-482): 1.21e-15: 78.2: 44.35
+	Hs
		714088 HS71L_HUMAN (1-643): 0: 960: 79.32		DNJB4_HUMAN (380-479): 7.53e-18: 86.7: 45.22
+	Hs
		503534 HSP7C_HUMAN (4-615): 0: 940: 79.25		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		714022 HS71L_HUMAN (1-643): 0: 960: 79.32		DNJB8_HUMAN (381-482): 1.21e-15: 78.2: 44.35
+	Dm
		1213525 HSP72_DROME (7-643): 0: 965: 71.14		Q9VHA8_DROME (4-282): 8.56e-12: 69.3: 13.77
+	Hs
		564188 HSP76_HUMAN (1-643): 0: 970: 100.00		RPAP3_HUMAN (2-223): 2.82e-09: 61.6: 11.92
+	Hs
		279272 HSP7C_HUMAN (4-615): 0: 940: 79.25		DNJB5_HUMAN (380-491): 5.82e-19: 90.1: 43.31
+	Hs
		564043 HSP76_HUMAN (1-643): 0: 970: 100.00		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79
+	Hs
		503512 HSP7C_HUMAN (4-615): 0: 940: 79.25		CDC27_HUMAN (4-128): 1.63e-15: 81.6: 20.80
+	Hs
		503738 HSP7C_HUMAN (4-615): 0: 940: 79.25		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79