HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: RHG01 (Q07960)
Rho GTPase-activating protein 1 (CDC42 GTPase-activating protein) (GTPase-activating protein rhoGAP) (Rho-related small GTPase protein activator) (Rho-type GTPase-activating protein 1) (p50-RhoGAP)
Gene: ARHGAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0007264 - small GTPase-mediated signal transduction GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 439
+	Hs
		993069 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		RHG01_HUMAN (1-439): 2.97e-164: 471: 100.00
+	Hs
		950946 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		RHG01_HUMAN (1-439): 2.97e-164: 471: 100.00
+	Mm
		925791 RAC1_MOUSE (10-195): 4.15e-80: 238: 63.98		RHG01_MOUSE (1-439): 4.64e-163: 468: 96.58
+	Hs
		1133703 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		RHG21_HUMAN (168-434): 3.18e-71: 246: 23.08
+	Hs
		1022689 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		RHG05_HUMAN (148-435): 5.93e-67: 233: 20.85
+	Hs
		64741 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		RHG32_HUMAN (180-433): 7.32e-64: 225: 21.56
+	Mm
		1194500 RHOJ_MOUSE (9-185): 3.89e-105: 303: 83.05		RHG33_MOUSE (164-438): 3.43e-63: 222: 22.38
+	Hs
		564562 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		RHG21_HUMAN (168-434): 3.18e-71: 246: 23.08
+	Hs
		951062 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		RHG21_HUMAN (168-434): 3.18e-71: 246: 23.08
+	Hs
		564503 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		RHG05_HUMAN (148-435): 5.93e-67: 233: 20.85
+	Hs
		950958 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		RHG05_HUMAN (148-435): 5.93e-67: 233: 20.85
+	Hs
		64652 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		RHG32_HUMAN (180-433): 7.32e-64: 225: 21.56
+	Hs
		200213 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		SRGP3_HUMAN (182-434): 2.44e-66: 231: 26.44
+	Mm
		925805 RAC1_MOUSE (10-195): 4.15e-80: 238: 63.98		RHG22_MOUSE (175-438): 2.95e-67: 229: 25.36
+	Hs
		64692 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		RHG32_HUMAN (180-433): 7.32e-64: 225: 21.56
+	Hs
		951115 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		RHG30_HUMAN (225-438): 1.57e-63: 223: 26.22
+	Hs
		64688 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		RHG32_HUMAN (180-433): 7.32e-64: 225: 21.56
+	Hs
		147862 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		RHG33_HUMAN (164-438): 1.47e-63: 224: 22.38
+	Mm
		925803 RAC1_MOUSE (10-195): 4.15e-80: 238: 63.98		RHG32_MOUSE (180-435): 3.64e-63: 222: 21.40
+	Mm
		925802 RAC1_MOUSE (10-195): 4.15e-80: 238: 63.98		CHIO_MOUSE (187-431): 1.39e-67: 220: 21.91