HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: GRDN (Q3V6T2)
Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1)
Gene: CCDC88A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007264 - small GTPase-mediated signal transduction GO:0032956 - regulation of actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 1871
+	Hs
		1113848 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		GRDN_HUMAN (1-1871): 2.19e-149: 509: 100.00
+	Hs
		951040 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		GRDN_HUMAN (1-1871): 2.19e-149: 509: 100.00
+	Hs
		925322 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		GRDN_HUMAN (1-1871): 2.19e-149: 509: 100.00
+	Hs
		894079 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		GRDN_HUMAN (1-1871): 2.19e-149: 509: 100.00
+	Hs
		254512 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		ROCK2_HUMAN (244-1010): 3.06e-09: 64.3: 20.76
+	Hs
		724776 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		MYH9_HUMAN (1-809): 2.13e-29: 130: 10.02
+	Hs
		724757 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		MYH9_HUMAN (1-809): 2.13e-29: 130: 10.02
+	Hs
		725138 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		MYH10_HUMAN (43-620): 1.66e-20: 101: 9.86
+	Hs
		725125 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		MYH10_HUMAN (43-620): 1.66e-20: 101: 9.86
+	Hs
		148653 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		CTRO_HUMAN (144-645): 2.42e-16: 88.1: 16.63
+	Hs
		564633 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		MY18A_HUMAN (599-1309): 1.19e-12: 75.9: 20.46
+	Hs
		950972 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		GOGA4_HUMAN (1253-1786): 2.42e-13: 78.1: 7.84
+	Hs
		925488 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		MY18A_HUMAN (599-1309): 1.19e-12: 75.9: 20.46
+	Hs
		254445 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		ROCK2_HUMAN (244-1010): 3.06e-09: 64.3: 20.76
+	Hs
		894274 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		MY18A_HUMAN (599-1309): 1.19e-12: 75.9: 20.46
+	Mm
		823530 RAC1_MOUSE (10-195): 4.15e-80: 238: 63.98		CTRO_MOUSE (468-1226): 3.12e-11: 71.2: 20.41
+	Mm
		823529 CDC42_MOUSE (9-193): 1.09e-78: 235: 67.57		CTRO_MOUSE (468-1226): 3.12e-11: 71.2: 20.41
+	Hs
		254472 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		ROCK2_HUMAN (244-1010): 3.06e-09: 64.3: 20.76
+	Hs
		254468 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		ROCK2_HUMAN (244-1010): 3.06e-09: 64.3: 20.76
+	Hs
		551652 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		DESP_HUMAN (244-1208): 1.11e-09: 66.2: 19.09