HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: FRS2 (Q8WU20)
Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (FGFR-signaling adaptor SNT) (Suc1-associated neurotrophic factor target 1) (SNT-1)
Gene: FRS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 508
+	Hs
		1259718 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		951184 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		925468 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		894251 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		900731 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		545522 RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		892505 RAC3_HUMAN (10-183): 9.1e-76: 227: 66.67		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		915865 RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		436429 RHOC_HUMAN (1-192): 1.16e-74: 225: 50.52		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		297840 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297827 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297823 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297820 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297812 RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297819 RAC3_HUMAN (10-183): 9.1e-76: 227: 66.67		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297822 RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297809 RHOC_HUMAN (1-192): 1.16e-74: 225: 50.52		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29