HitPredict

Interactor 1: HMGA1 (P17096)
High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility group AT-hook protein 1) (High mobility group protein A1) (High mobility group protein R)
Gene: HMGA1

Interactor 2: H2A1C (Q93077)
Histone H2A type 1-C (H2A-clustered histone 6) (Histone H2A/l)
Gene: H2AC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008285 - negative regulation of cell population proliferation GO:0030527 - structural constituent of chromatin
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 107 Hs			1 130
+	Hs
		564939 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2A2A_HUMAN (1-130): 9.4e-68: 202: 98.46
+	Hs
		391537 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2A1B_HUMAN (1-130): 1.52e-67: 201: 98.46
+	Hs
		470258 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2A1_HUMAN (1-130): 1.29e-67: 201: 98.46
+	Hs
		564997 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2A1H_HUMAN (1-128): 7.48e-67: 199: 98.44
+	Hs
		564959 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2A2B_HUMAN (1-130): 3.14e-66: 198: 95.39
+	Hs
		555282 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2AX_HUMAN (1-130): 1.1e-63: 192: 89.55