HitPredict

Interactor 1: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Interactor 2: EPHB3 (P54753)
Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) (EPH-like kinase 2) (Embryonic kinase 2) (EK2) (hEK2) (Tyrosine-protein kinase TYRO6)
Gene: EPHB3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 998
+	Hs
		566985 CXA1_HUMAN (1-382): 0: 545: 100.00		EPHA4_HUMAN (17-993): 0: 1155: 56.95
+	Hs
		566936 CXA1_HUMAN (1-382): 0: 545: 100.00		EPHA3_HUMAN (35-996): 0: 1154: 56.44
+	Hs
		566935 CXA1_HUMAN (1-382): 0: 545: 100.00		EPHA2_HUMAN (36-991): 0: 1041: 47.27
+	Hs
		434822 CXB1_HUMAN (3-285): 8.15e-116: 339: 38.62		EPHB1_HUMAN (38-993): 0: 1199: 70.81
+	Hs
		872409 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		EPHB3_HUMAN (1-998): 0: 1227: 100.00
+	Hs
		1072544 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		EPHA7_HUMAN (15-998): 0: 1158: 54.18
+	Hs
		665269 CXB7_HUMAN (4-234): 1.64e-104: 309: 41.81		EPHA2_HUMAN (36-991): 0: 1041: 47.27
+	Hs
		665282 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		EPHA2_HUMAN (36-991): 0: 1041: 47.27
+	Hs
		434812 CXB1_HUMAN (3-285): 8.15e-116: 339: 38.62		EPHA1_HUMAN (15-987): 0: 960: 42.71
+	Hs
		411289 CXA1_HUMAN (1-382): 0: 545: 100.00		INSR_HUMAN (295-957): 3.47e-142: 461: 24.71
+	Hs
		435527 CXA1_HUMAN (1-382): 0: 545: 100.00		IGF1R_HUMAN (276-894): 4.3e-141: 458: 25.79
+	Hs
		411435 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		INSR_HUMAN (295-957): 3.47e-142: 461: 24.71
+	Hs
		412232 CXB7_HUMAN (4-234): 1.64e-104: 309: 41.81		FYN_HUMAN (627-893): 1.18e-61: 221: 42.54