HitPredict

Interactor 1: HXB9 (P17482)
Homeobox protein Hox-B9 (Homeobox protein Hox-2.5) (Homeobox protein Hox-2E)
Gene: HOXB9

Interactor 2: VSX1 (Q9NZR4)
Visual system homeobox 1 (Homeodomain protein RINX) (Retinal inner nuclear layer homeobox protein) (Transcription factor VSX1)
Gene: VSX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Homeodomain~Homeodomain
Common GO terms	GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:1990837 - sequence-specific double-stranded DNA binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 250 Hs			1 365
+	Hs
		620235 MEOX1_HUMAN (31-247): 1.89e-37: 133: 27.75		PAX3_HUMAN (112-233): 1.46e-36: 139: 45.60
+	Hs
		568043 HXB6_HUMAN (68-245): 3.12e-37: 132: 30.85		ALX4_HUMAN (99-224): 1.98e-36: 138: 41.79
+	Mm
		453073 HXA9_MOUSE (1-250): 2.44e-43: 149: 45.19		PAX6_MOUSE (116-362): 8.15e-30: 120: 24.22
+	Mm
		192283 HXA10_MOUSE (16-246): 5.66e-34: 128: 34.76		ALX4_MOUSE (96-224): 2.19e-36: 137: 43.41
+	Mm
		192281 ALX4_MOUSE (2-250): 4.49e-30: 117: 18.22		PAX3_MOUSE (112-233): 1.3e-36: 139: 45.60
+	Mm
		192275 ALX4_MOUSE (2-250): 4.49e-30: 117: 18.22		ALX4_MOUSE (96-224): 2.19e-36: 137: 43.41
+	Hs
		829985 HXA1_HUMAN (10-247): 1.1e-30: 118: 24.17		PITX2_HUMAN (127-226): 1.3e-35: 133: 42.00
+	Mm
		192276 ALX4_MOUSE (2-250): 4.49e-30: 117: 18.22		RX_MOUSE (98-234): 2.31e-35: 133: 40.26
+	Mm
		192291 ALX4_MOUSE (2-250): 4.49e-30: 117: 18.22		PRRX1_MOUSE (115-249): 2.46e-36: 133: 33.10
+	Hs
		678891 HXC8_HUMAN (7-248): 4.5e-31: 116: 29.34		LHX2_HUMAN (78-301): 8.5e-35: 133: 24.11
+	Hs
		679014 HXC9_HUMAN (1-234): 1.05e-33: 124: 44.31		HXD1_HUMAN (34-267): 4.67e-32: 124: 19.23
+	Hs
		678889 MEOX1_HUMAN (31-247): 1.89e-37: 133: 27.75		HXC8_HUMAN (34-232): 1.79e-28: 112: 17.91
+	Hs
		641328 HXC9_HUMAN (1-234): 1.05e-33: 124: 44.31		PAX6_HUMAN (116-362): 8.15e-30: 120: 24.22
+	Hs
		238103 HXA1_HUMAN (10-247): 1.1e-30: 118: 24.17		LMX1B_HUMAN (122-328): 2.51e-30: 121: 20.35
+	Hs
		641341 HXA1_HUMAN (10-247): 1.1e-30: 118: 24.17		PAX6_HUMAN (116-362): 8.15e-30: 120: 24.22
+	Hs
		446864 HXA5_HUMAN (7-249): 5.95e-32: 119: 24.32		HXD4_HUMAN (43-248): 6.12e-30: 117: 20.36
+	Hs
		641327 HXC8_HUMAN (7-248): 4.5e-31: 116: 29.34		PAX6_HUMAN (116-362): 8.15e-30: 120: 24.22
+	Hs
		453048 HXA5_HUMAN (7-249): 5.95e-32: 119: 24.32		HXB7_HUMAN (39-234): 4.35e-29: 113: 23.47
+	Hs
		453052 HXA7_HUMAN (8-248): 2.61e-31: 117: 25.73		HXB7_HUMAN (39-234): 4.35e-29: 113: 23.47