HitPredict

Interactor 1: KAPCA (P17612)
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)
Gene: PRKACA

Interactor 2: CNTRL (Q7Z7A1)
Centriolin (Centrosomal protein 1) (Centrosomal protein of 110 kDa) (Cep110)
Gene: CNTRL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26638075
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 351 Hs			1 2325
+	Hs
		610802 KAPCB_HUMAN (1-351): 7.27e-164: 463: 92.88		MYH4_HUMAN (31-955): 3.1e-32: 140: 10.27
+	Mm
		554927 KPCE_MOUSE (9-351): 4.22e-141: 419: 36.70		MYH7_MOUSE (320-1387): 2.06e-39: 164: 11.55
+	Hs
		568568 KAPCA_HUMAN (1-351): 9.98e-166: 467: 100.00		MYH10_HUMAN (435-1535): 1.74e-23: 111: 13.16
+	Hs
		528359 KAPCB_HUMAN (1-351): 7.27e-164: 463: 92.88		MYH6_HUMAN (48-865): 4.42e-22: 107: 10.36
+	Hs
		568567 KAPCA_HUMAN (1-351): 9.98e-166: 467: 100.00		MYH9_HUMAN (428-1535): 9.41e-20: 99.6: 11.25
+	Hs
		623875 KPCL_HUMAN (6-351): 1.39e-145: 428: 36.59		PLEC_HUMAN (3-1210): 2.76e-30: 134: 9.08
+	Hs
		522538 KAPCB_HUMAN (1-351): 7.27e-164: 463: 92.88		MYH1_HUMAN (57-648): 4.13e-17: 90.8: 10.72
+	Hs
		610795 KAPCB_HUMAN (1-351): 7.27e-164: 463: 92.88		MYH2_HUMAN (57-648): 1.64e-16: 88.9: 9.88
+	Hs
		518814 KAPCA_HUMAN (1-351): 9.98e-166: 467: 100.00		TPR_HUMAN (1948-2320): 1.22e-11: 72.7: 10.70
+	Mm
		554901 KPCE_MOUSE (9-351): 4.22e-141: 419: 36.70		MYH6_MOUSE (54-885): 9.9e-25: 115: 9.84
+	Hs
		681696 AKT1_HUMAN (7-347): 2.89e-149: 430: 38.79		MYH9_HUMAN (428-1535): 9.41e-20: 99.6: 11.25
+	Hs
		551616 AKT1_HUMAN (7-347): 2.89e-149: 430: 38.79		DESP_HUMAN (1318-1769): 1.22e-16: 89.6: 15.24
+	Hs
		724784 KPCE_HUMAN (9-351): 6.36e-141: 418: 36.42		MYH9_HUMAN (428-1535): 9.41e-20: 99.6: 11.25
+	Hs
		551672 KPCE_HUMAN (9-351): 6.36e-141: 418: 36.42		DESP_HUMAN (1318-1769): 1.22e-16: 89.6: 15.24
+	Dm
		397193 KPC1_DROME (3-351): 3.07e-140: 414: 36.11		MYSN_DROME (1328-2081): 7.94e-09: 63.5: 19.28
+	Hs
		116964 SGK1_HUMAN (34-342): 1.03e-85: 267: 42.54		MYH1_HUMAN (57-648): 4.13e-17: 90.8: 10.72