Interactor 1: CAN2 (P17655)
Calpain-2 catalytic subunit (EC 3.4.22.53) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (Calpain large polypeptide L2) (Calpain-2 large subunit) (Millimolar-calpain) (M-calpain)
Gene: CAPN2

Interactor 2: MK01 (P28482)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: MAPK1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 1.00 0.735

The method score is based on:

Property Details
Experiments 14993287
Identification Methods enzymatic study, protein kinase assay
Interaction Type direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_8~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 700
Hs

1 360
+ Mm
+ Dm

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Last updated: 15 Jul 2024