HitPredict

Interactor 1: CEBPB (P17676)
CCAAT/enhancer-binding protein beta (C/EBP beta) (Liver activator protein) (LAP) (Liver-enriched inhibitory protein) (LIP) (Nuclear factor NF-IL6) (Transcription factor 5) (TCF-5)
Gene: CEBPB

Interactor 2: EGR1 (P18146)
Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24)
Gene: EGR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 0.60 0.606

The method score is based on:

Property Details
Experiments 22260630, 12947119
Identification Methods affinity chromatography technology, two hybrid, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
and 12 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 345
Hs

1 543
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024