Protein: T2FB
Transcription initiation factor IIF subunit beta (TFIIF medium subunit) (TFIIF-beta) (Transcription factor G 54 kDa subunit)

Gene: T2FB, TFG2
Organism: Saccharomyces cerevisiae S288C
Interactions: 71
UniProt ID: P41896

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0000993 - RNA polymerase II complex binding
GO:0001174 - transcriptional start site selection at RNA polymerase II promoter
GO:0003677 - DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

470545

RPB2
DNA-directed RNA polymerase II subunit RPB2

8

2

Small-scale

0.969

High

836526

T2FA
Transcription initiation factor IIF subunit alpha

13

0

Small-scale

0.927

High

707382

TF2B
Transcription initiation factor IIB

4

1

Small-scale

0.870

High

594421

RPB3
DNA-directed RNA polymerase II subunit RPB3

13

3

Small-scale

0.757

High

402034

RPB1
DNA-directed RNA polymerase II subunit RPB1

11

2

Small-scale

0.756

High

763337

TAF14
Transcription initiation factor TFIID subunit 14

11

2

Small-scale

0.754

High

806934

RPB11
DNA-directed RNA polymerase II subunit RPB11

8

1

Small-scale

0.746

High

632174

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

7

2

Small-scale

0.745

High

699961

RPB9
DNA-directed RNA polymerase II subunit RPB9

6

3

Small-scale

0.730

High

757333

RPB7
DNA-directed RNA polymerase II subunit RPB7

6

1

Small-scale

0.729

High

632265

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

5

1

Small-scale

0.709

High

632096

RPB4
DNA-directed RNA polymerase II subunit RPB4

6

0

Small-scale

0.695

High

796089

IMB2
Importin subunit beta-2

3

1

Small-scale

0.672

High

632352

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

3

1

Small-scale

0.656

High

645065

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

4

0

Small-scale

0.653

High

740804

MED18
Mediator of RNA polymerase II transcription subunit 18

4

0

Small-scale

0.651

High

782136

T2EB
Transcription initiation factor IIE subunit beta

1

1

Small-scale

0.647

High

561489

TBP
TATA-box-binding protein

1

1

Small-scale

0.646

High

694569

SPT5
Transcription elongation factor SPT5

3

0

High-throughput

0.628

High

740417

MED17
Mediator of RNA polymerase II transcription subunit 17

3

0

Small-scale

0.606

High

823709

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

2

2

Small-scale

0.584

High

740463

MED22
Mediator of RNA polymerase II transcription subunit 22

2

0

Small-scale

0.569

High

757587

MED20
Mediator of RNA polymerase II transcription subunit 20

2

0

Small-scale

0.559

High

798600

PAF1
RNA polymerase II-associated protein 1

2

0

Small-scale

0.547

High

836558

CDC73
Cell division control protein 73

2

0

Small-scale

0.547

High

815473

RSP5
E3 ubiquitin-protein ligase RSP5

1

2

High-throughput

0.536

High

547875

NHP6B
Non-histone chromosomal protein 6B

1

1

Small-scale

0.527

High

836550

UBC13
Ubiquitin-conjugating enzyme E2 13

1

0

High-throughput

0.518

High

441377

KAPB
cAMP-dependent protein kinase type 2

1

0

High-throughput

0.513

High

734689

IMB3
Importin subunit beta-3

1

1

Small-scale

0.501

High

781055

T2EA
Transcription initiation factor IIE subunit alpha

1

1

Small-scale

0.501

High

836551

IMB5
Importin subunit beta-5

1

3

Small-scale

0.501

High

836553

KA120
Importin beta-like protein KAP120

1

4

Small-scale

0.501

High

836554

SXM1
Importin beta SMX1

1

3

Small-scale

0.501

High

836548

UPF3
Nonsense-mediated mRNA decay protein 3

1

0

High-throughput

0.493

High

547804

NHP6A
Non-histone chromosomal protein 6A

1

1

Small-scale

0.481

High

797710

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

Small-scale

0.479

High

804025

MED6
Mediator of RNA polymerase II transcription subunit 6

1

0

Small-scale

0.479

High

836564

MED11
Mediator of RNA polymerase II transcription subunit 11

1

0

Small-scale

0.479

High

736664

ASF1
Histone chaperone ASF1

1

1

Small-scale

0.479

High

792101

GBLP
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.479

High

836545

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

1

High-throughput

0.479

High

392895

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.460

High

557732

SRS2
ATP-dependent DNA helicase SRS2

1

0

High-throughput

0.458

High

605905

HPR1
THO complex subunit HPR1

1

0

Small-scale

0.458

High

624923

MED15
Mediator of RNA polymerase II transcription subunit 15

1

0

Small-scale

0.458

High

661173

SPT6
Transcription elongation factor SPT6

1

0

High-throughput

0.458

High

726225

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

1

0

Small-scale

0.458

High

748297

SPT4
Transcription elongation factor SPT4

1

0

High-throughput

0.458

High

751212

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

Small-scale

0.458

High

758223

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

High-throughput

0.458

High

836547

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

836555

SSL1
General transcription and DNA repair factor IIH subunit SSL1

1

0

Small-scale

0.458

High

836556

IWS1
Transcription factor SPN1

1

0

High-throughput

0.458

High

836557

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

836559

ASR1
Alcohol-sensitive RING finger protein 1

1

0

High-throughput

0.458

High

836560

IWR1
RNA polymerase II nuclear localization protein IWR1

1

0

High-throughput

0.458

High

836562

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

454582

TFS2
Transcription elongation factor S-II

1

3

Small-scale

0.445

High

806428

CTF8
Chromosome transmission fidelity protein 8

1

0

High-throughput

0.438

High

524264

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

836561

TFB4
General transcription and DNA repair factor IIH subunit TFB4

1

0

Small-scale

0.426

High

836563

GDIR
Rho GDP-dissociation inhibitor

1

0

High-throughput

0.251

Low

148879

CET1
mRNA-capping enzyme subunit beta

1

0

High-throughput

0.249

Low

512497

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

753430

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

797752

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

836546

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.249

Low

836549

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

836552

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

820877

SIP5
Protein SIP5

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025