Interactor 1: HLAG (P17693)
HLA class I histocompatibility antigen, alpha chain G (HLA G antigen) (MHC class I antigen G) [Cleaved into: Soluble HLA class I histocompatibility antigen, alpha chain G (sHLA-G)]
Gene: HLA-G

Interactor 2: HLAG (P17693)
HLA class I histocompatibility antigen, alpha chain G (HLA G antigen) (MHC class I antigen G) [Cleaved into: Soluble HLA class I histocompatibility antigen, alpha chain G (sHLA-G)]
Gene: HLA-G

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.941

The method score is based on:

Property Details
Experiments 12874224, 12454284, 28348268, 22802125, 16455647, 18550825
Identification Methods affinity chromatography technology, biochemical, molecular sieving, electron microscopy, electrophoretic mobility-based method, comigration in sds page, comigration in non denaturing gel electrophoresis
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~C1-set, C1-set~MHC_I, MHC_I~MHC_I
Common GO terms GO:0000139 - Golgi membrane
GO:0001915 - negative regulation of T cell mediated cytotoxicity
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0002451 - peripheral B cell tolerance induction
GO:0002476 - antigen processing and presentation of endogenous peptide antigen via MHC class Ib
and 38 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 338
Hs

1 338
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Last updated: 15 Jul 2024