Protein: UTP14
U3 small nucleolar RNA-associated protein 14 (U3 snoRNA-associated protein 14) (U three protein 14)

Gene: UTP14
Organism: Saccharomyces cerevisiae S288C
Interactions: 227
UniProt ID: Q04500

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1046023

DHR1
Probable ATP-dependent RNA helicase DHR1

11

2

Small-scale

0.757

High

1046799

NOC4
Nucleolar complex protein 4

6

2

Small-scale

0.721

High

753579

RS3A1
Small ribosomal subunit protein eS1A

2

2

High-throughput

0.716

High

865166

MPP10
U3 small nucleolar RNA-associated protein MPP10

5

1

Small-scale

0.709

High

844604

UTP10
U3 small nucleolar RNA-associated protein 10

5

0

High-throughput

0.680

High

925192

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

4

2

Small-scale

0.676

High

1046832

NOP58
Nucleolar protein 58

4

3

Small-scale

0.676

High

1046838

PNO1
Pre-rRNA-processing protein PNO1

3

2

High-throughput

0.661

High

677556

KRR1
KRR1 small subunit processome component

4

0

High-throughput

0.659

High

924626

NAT10
RNA cytidine acetyltransferase

4

0

High-throughput

0.659

High

754329

DCA13
Protein SOF1

3

10

High-throughput

0.658

High

1046837

NOP14
Nucleolar complex protein 14

3

1

High-throughput

0.650

High

918818

UTP22
U3 small nucleolar RNA-associated protein 22

3

0

High-throughput

0.643

High

798304

ENP1
Essential nuclear protein 1

3

2

High-throughput

0.640

High

836202

DIM1
Dimethyladenosine transferase

3

1

Small-scale

0.640

High

864514

MTR4
ATP-dependent RNA helicase DOB1

3

2

Small-scale

0.640

High

1046791

UTP21
U3 small nucleolar RNA-associated protein 21

3

8

Small-scale

0.640

High

1046802

UTP4
U3 small nucleolar RNA-associated protein 4

3

7

Small-scale

0.640

High

1046824

RRP6
Exosome complex exonuclease RRP6

3

2

High-throughput

0.640

High

1036405

UTP6
U3 small nucleolar RNA-associated protein 6

3

0

High-throughput

0.630

High

1046823

SAS10
Something about silencing protein 10

3

0

High-throughput

0.630

High

823381

UTP18
U3 small nucleolar RNA-associated protein 18

3

0

High-throughput

0.628

High

689652

RS7A
Small ribosomal subunit protein eS7A

2

2

High-throughput

0.620

High

632737

DBP4
ATP-dependent RNA helicase HCA4

2

4

High-throughput

0.614

High

779158

DHR2
Probable ATP-dependent RNA helicase DHR2

2

2

High-throughput

0.614

High

1043276

HAS1
ATP-dependent RNA helicase HAS1

2

4

High-throughput

0.614

High

923981

CSL4
Exosome complex component CSL4

3

0

High-throughput

0.613

High

1046786

RRP5
rRNA biogenesis protein RRP5

3

0

High-throughput

0.613

High

782443

RPF2
Ribosome biogenesis protein RPF2

2

1

High-throughput

0.611

High

917475

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

2

1

High-throughput

0.611

High

806568

UTP9
U3 small nucleolar RNA-associated protein 9

3

0

High-throughput

0.606

High

503232

RS22A
Small ribosomal subunit protein uS8A

3

2

High-throughput

0.585

High

436166

RS13
Small ribosomal subunit protein uS15

2

1

High-throughput

0.584

High

442103

RS14A
Small ribosomal subunit protein uS11A

2

1

High-throughput

0.584

High

512641

RS6A
Small ribosomal subunit protein eS6A

2

1

High-throughput

0.584

High

678455

PWP2
Periodic tryptophan protein 2

2

4

High-throughput

0.584

High

747045

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

2

2

High-throughput

0.584

High

763623

UTP20
U3 small nucleolar RNA-associated protein 20

2

1

High-throughput

0.584

High

782101

RL1D1
Ribosome biogenesis protein UTP30

2

2

High-throughput

0.584

High

804746

RRP4
Exosome complex component RRP4

2

1

High-throughput

0.584

High

814381

NOC2
Nucleolar complex protein 2

2

1

High-throughput

0.584

High

817627

UTP7
U3 small nucleolar RNA-associated protein 7

2

3

High-throughput

0.584

High

852598

ROK1
ATP-dependent RNA helicase ROK1

2

1

High-throughput

0.584

High

863133

RRP41
Exosome complex component SKI6

2

3

High-throughput

0.584

High

870681

RS7B
Small ribosomal subunit protein eS7B

2

2

High-throughput

0.584

High

918889

RRP46
Exosome complex component RRP46

2

3

High-throughput

0.584

High

1039847

UTP17
NET1-associated nuclear protein 1

2

10

High-throughput

0.584

High

1042225

TOM1
E3 ubiquitin-protein ligase TOM1

2

1

High-throughput

0.584

High

1045101

UTP5
U3 small nucleolar RNA-associated protein 5

2

2

High-throughput

0.584

High

1046245

UTP15
U3 small nucleolar RNA-associated protein 15

2

8

High-throughput

0.584

High

1046787

FCF1
rRNA-processing protein FCF1

2

2

High-throughput

0.584

High

1046788

RRP45
Exosome complex component RRP45

2

3

High-throughput

0.584

High

1046790

UTP13
U3 small nucleolar RNA-associated protein 13

2

12

High-throughput

0.584

High

1046798

RRP9
Ribosomal RNA-processing protein 9

2

12

High-throughput

0.584

High

1046800

BFR2
Protein BFR2

2

1

High-throughput

0.584

High

1046808

RRP44
Exosome complex exonuclease DIS3

2

1

High-throughput

0.584

High

1046819

BMS1
Ribosome biogenesis protein BMS1

2

2

High-throughput

0.584

High

1046825

MAK21
Ribosome biogenesis protein MAK21

2

2

High-throughput

0.584

High

1046826

UTP12
U3 small nucleolar RNA-associated protein 12

2

5

High-throughput

0.584

High

1046827

RRP42
Exosome complex component RRP42

2

3

High-throughput

0.584

High

1046830

NOP56
Nucleolar protein 56

2

3

High-throughput

0.584

High

514828

RS18A
Small ribosomal subunit protein uS13A

2

0

High-throughput

0.559

High

672943

RRP43
Exosome complex component RRP43

2

0

High-throughput

0.559

High

673224

RRP7
Ribosomal RNA-processing protein 7

2

0

High-throughput

0.559

High

758404

UTP11
U3 small nucleolar RNA-associated protein 11

2

0

High-throughput

0.559

High

804955

LRP1
Exosome complex protein LRP1

2

0

High-throughput

0.559

High

818338

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

2

0

High-throughput

0.559

High

825557

UTP25
U3 small nucleolar RNA-associated protein 25

2

0

High-throughput

0.559

High

826208

FAF1
Protein FAF1

2

0

High-throughput

0.559

High

871051

NOL10
Ribosome biogenesis protein ENP2

2

0

High-throughput

0.559

High

871121

MTR3
Exosome complex component MTR3

2

0

High-throughput

0.559

High

874519

RS12
Small ribosomal subunit protein eS12

2

0

High-throughput

0.559

High

919166

UTP8
U3 small nucleolar RNA-associated protein 8

2

0

High-throughput

0.559

High

923250

ESF2
Pre-rRNA-processing protein ESF2

2

0

High-throughput

0.559

High

1046796

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

2

0

High-throughput

0.559

High

1046797

ESF1
Pre-rRNA-processing protein ESF1

2

0

High-throughput

0.559

High

1046807

RCL1
rRNA processing protein RCL1

2

0

High-throughput

0.559

High

1046811

RRP40
Exosome complex component RRP40

2

0

High-throughput

0.559

High

1046815

UTP16
U3 small nucleolar RNA-associated protein 16

2

0

High-throughput

0.559

High

1046821

FCF2
rRNA-processing protein FCF2

2

0

High-throughput

0.559

High

1046834

RRP12
Ribosomal RNA-processing protein 12

2

0

High-throughput

0.559

High

1046835

EFG1P
rRNA-processing protein EFG1

2

0

High-throughput

0.559

High

655515

RS3A2
Small ribosomal subunit protein eS1B

1

2

High-throughput

0.553

High

586016

CSK21
Casein kinase II subunit alpha

1

4

High-throughput

0.541

High

455252

RS19A
Small ribosomal subunit protein eS19A

2

1

High-throughput

0.533

High

826818

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.533

High

673590

NLE1
Ribosome assembly protein 4

1

11

High-throughput

0.515

High

1039035

IMA1
Importin subunit alpha

1

0

High-throughput

0.493

High

149949

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

435631

RS9B
Small ribosomal subunit protein uS4B

1

2

High-throughput

0.479

High

585367

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.479

High

633188

MAK11
Protein MAK11

1

10

High-throughput

0.479

High

637280

PWP1
Periodic tryptophan protein 1

1

6

High-throughput

0.479

High

646530

RAD53
Serine/threonine-protein kinase RAD53

1

4

High-throughput

0.479

High

674830

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

680050

CDC48
Cell division control protein 48

1

5

High-throughput

0.479

High

708784

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

High-throughput

0.479

High

735156

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

746671

DRS1
ATP-dependent RNA helicase DRS1

1

4

High-throughput

0.479

High

747571

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

750145

MRT4
Ribosome assembly factor MRT4

1

2

High-throughput

0.479

High

763115

RRP1
Ribosomal RNA-processing protein 1

1

2

High-throughput

0.479

High

763293

SGS1
ATP-dependent helicase SGS1

1

2

High-throughput

0.479

High

781651

DBP7
ATP-dependent RNA helicase DBP7

1

3

High-throughput

0.479

High

791106

NOP4
Nucleolar protein 4

1

1

High-throughput

0.479

High

793528

MAK5
ATP-dependent RNA helicase MAK5

1

5

High-throughput

0.479

High

802769

RRP3
ATP-dependent rRNA helicase RRP3

1

4

High-throughput

0.479

High

802902

DBP8
ATP-dependent RNA helicase DBP8

1

4

High-throughput

0.479

High

803931

CIC1
Proteasome-interacting protein CIC1

1

2

High-throughput

0.479

High

805090

RPF1
Ribosome production factor 1

1

1

High-throughput

0.479

High

816550

SNU13
13 kDa ribonucleoprotein-associated protein

1

4

High-throughput

0.479

High

816900

NUG1
Nuclear GTP-binding protein NUG1

1

3

High-throughput

0.479

High

827603

RLP7
Ribosome biogenesis protein RLP7

1

2

High-throughput

0.479

High

830179

NOP2
25S rRNA

1

1

High-throughput

0.479

High

918986

PESC
Pescadillo homolog

1

2

High-throughput

0.479

High

923022

DBP6
ATP-dependent RNA helicase DBP6

1

5

High-throughput

0.479

High

923061

TR112
Multifunctional methyltransferase subunit TRM112

1

1

Small-scale

0.479

High

923203

NOG2
Nucleolar GTP-binding protein 2

1

3

High-throughput

0.479

High

924843

NOP15
Ribosome biogenesis protein 15

1

4

High-throughput

0.479

High

1039627

NOG1
Nucleolar GTP-binding protein 1

1

1

High-throughput

0.479

High

1046784

UTP14
U3 small nucleolar RNA-associated protein 14

1

9

High-throughput

0.479

High

1046785

ERB1
Ribosome biogenesis protein ERB1

1

9

High-throughput

0.479

High

1046792

MRD1
Multiple RNA-binding domain-containing protein 1

1

1

High-throughput

0.479

High

1046795

DBP9
ATP-dependent RNA helicase DBP9

1

4

High-throughput

0.479

High

1046806

RLP24
Ribosome biogenesis protein RLP24

1

2

High-throughput

0.479

High

1046809

NOP12
Nucleolar protein 12

1

2

High-throughput

0.479

High

1046810

BRX1
Ribosome biogenesis protein BRX1

1

5

High-throughput

0.479

High

1046818

RRS1
Regulator of ribosome biosynthesis

1

2

High-throughput

0.479

High

1046820

YTM1
Ribosome biogenesis protein YTM1

1

12

High-throughput

0.479

High

1046822

FAL1
ATP-dependent RNA helicase FAL1

1

1

High-throughput

0.479

High

755172

GCN1
eIF-2-alpha kinase activator GCN1

1

1

High-throughput

0.470

High

534140

MAK16
Protein MAK16

1

0

High-throughput

0.458

High

632593

DBP3
ATP-dependent RNA helicase DBP3

1

0

High-throughput

0.458

High

678255

BUD23
18S rRNA

1

0

Small-scale

0.458

High

688945

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.458

High

692619

NSR1
Nuclear localization sequence-binding protein

1

0

High-throughput

0.458

High

758253

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

High-throughput

0.458

High

780316

EBP2
rRNA-processing protein EBP2

1

0

High-throughput

0.458

High

781260

RL14A
Large ribosomal subunit protein eL14A

1

0

High-throughput

0.458

High

804659

SSF1
Ribosome biogenesis protein SSF1

1

0

High-throughput

0.458

High

808304

RRP8
25S rRNA

1

0

High-throughput

0.458

High

811160

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.458

High

816794

NOP16
Nucleolar protein 16

1

0

High-throughput

0.458

High

825078

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

843272

KRI1
Protein KRI1

1

0

High-throughput

0.458

High

864958

NOP9
Nucleolar protein 9

1

0

High-throughput

0.458

High

865415

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.458

High

917556

NSA1
Ribosome biogenesis protein NSA1

1

0

High-throughput

0.458

High

1046470

BUD22
Bud site selection protein 22

1

0

High-throughput

0.458

High

1046509

PUF6
Pumilio homology domain family member 6

1

0

High-throughput

0.458

High

1046789

RSA3
Ribosome assembly protein 3

1

0

High-throughput

0.458

High

1046793

SGD1
Suppressor of glycerol defect protein 1

1

0

High-throughput

0.458

High

1046804

NOP6
Nucleolar protein 6

1

0

High-throughput

0.458

High

1046812

NOP8
60S ribosome subunit biogenesis protein NOP8

1

0

High-throughput

0.458

High

1046813

NOB1
20S-pre-rRNA D-site endonuclease NOB1

1

0

High-throughput

0.458

High

1046828

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.458

High

1046831

RRP36
rRNA biogenesis protein RRP36

1

0

High-throughput

0.458

High

1046816

ESA1
Histone acetyltransferase ESA1

1

1

Small-scale

0.457

High

525095

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

527633

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

546212

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

742361

HSP7F
Heat shock protein homolog SSE1

1

7

High-throughput

0.445

High

752712

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

816396

HSP7E
Heat shock protein SSC3, mitochondrial

1

3

High-throughput

0.445

High

381254

H2B1
Histone H2B.1

1

3

High-throughput

0.437

High

381630

H2B2
Histone H2B.2

1

3

High-throughput

0.437

High

383194

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.437

High

383889

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.437

High

419501

H2A1
Histone H2A.1

1

3

High-throughput

0.437

High

419867

H2A2
Histone H2A.2

1

3

High-throughput

0.437

High

427439

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.437

High

427750

RLA2
Large ribosomal subunit protein P2A

1

1

High-throughput

0.437

High

432697

RL7A
Large ribosomal subunit protein uL30A

1

2

High-throughput

0.437

High

433288

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.437

High

433840

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.437

High

434440

RL15A
Large ribosomal subunit protein eL15A

1

1

High-throughput

0.437

High

435351

RS3
Small ribosomal subunit protein uS3

1

1

Small-scale

0.437

High

436513

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

1

High-throughput

0.437

High

504407

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

513211

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

513574

RL1A
Large ribosomal subunit protein uL1A

1

3

High-throughput

0.437

High

514190

RS16B
Small ribosomal subunit protein uS9B

1

1

High-throughput

0.437

High

531882

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.437

High

570139

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.437

High

570304

RS17B
Small ribosomal subunit protein eS17B

1

2

High-throughput

0.437

High

601127

RL8A
Large ribosomal subunit protein eL8A

1

4

High-throughput

0.437

High

708129

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

712667

RL8B
Large ribosomal subunit protein eL8B

1

4

High-throughput

0.437

High

778523

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.437

High

792238

GBLP
Small ribosomal subunit protein RACK1

1

8

High-throughput

0.437

High

812639

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

918334

RL26B
Large ribosomal subunit protein uL24B

1

2

High-throughput

0.437

High

1033555

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.437

High

1046794

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

1046817

RS10A
Small ribosomal subunit protein eS10A

1

4

High-throughput

0.437

High

1046833

RL13A
Large ribosomal subunit protein eL13A

1

1

High-throughput

0.437

High

1046836

RS22B
Small ribosomal subunit protein uS8B

1

2

High-throughput

0.437

High

590720

HSP26
Heat shock protein 26

1

1

High-throughput

0.407

High

811389

CAJ1
Protein CAJ1

1

1

High-throughput

0.407

High

918385

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

1

1

High-throughput

0.407

High

1046801

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

3

High-throughput

0.407

High

1046805

CMS1
Protein CMS1

2

0

High-throughput

0.305

High

1046803

CSR1
Phosphatidylinositol transfer protein CSR1

1

0

High-throughput

0.269

Low

1046829

ISA2
Iron-sulfur assembly protein 2

1

0

High-throughput

0.269

Low

154228

RL36B
Large ribosomal subunit protein eL36B

1

0

High-throughput

0.249

Low

410332

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

433078

RL6B
Large ribosomal subunit protein eL6B

1

0

High-throughput

0.249

Low

511288

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.249

Low

512151

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.249

Low

513410

RL23B
Large ribosomal subunit protein uL14B

1

0

High-throughput

0.249

Low

513771

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.249

Low

514362

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.249

Low

569860

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.249

Low

644986

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.249

Low

645531

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.249

Low

684840

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.249

Low

751480

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.249

Low

792939

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.249

Low

802380

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

804124

RPP1
Ribonuclease P/MRP protein subunit RPP1

1

0

High-throughput

0.249

Low

836134

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.249

Low

922951

MPP6
M-phase phosphoprotein 6 homolog

1

0

High-throughput

0.249

Low

1043919

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

Small-scale

0.249

Low

1046296

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.249

Low

1046814

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

671704

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025