HitPredict

Interactor 1: PTN2 (P17706)
Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP)
Gene: PTPN2

Interactor 2: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 415 Hs			1 191
+	Hs
		545197 PTN2_HUMAN (1-415): 2.43e-175: 497: 100.00		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		570514 PTN2_HUMAN (1-415): 2.43e-175: 497: 100.00		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		436150 PTN2_HUMAN (1-415): 2.43e-175: 497: 100.00		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Hs
		573655 PTN1_HUMAN (4-413): 1e-158: 455: 51.93		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		573659 PTN1_HUMAN (4-413): 1e-158: 455: 51.93		RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00
+	Hs
		545198 PTN1_HUMAN (4-413): 1e-158: 455: 51.93		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		573644 PTN1_HUMAN (4-413): 1e-158: 455: 51.93		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		573648 PTN1_HUMAN (4-413): 1e-158: 455: 51.93		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		436151 PTN1_HUMAN (4-413): 1e-158: 455: 51.93		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Hs
		573643 PTN1_HUMAN (4-413): 1e-158: 455: 51.93		RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88
+	Hs
		925235 PTPRJ_HUMAN (4-307): 5.14e-125: 393: 31.73		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		950951 PTPRJ_HUMAN (4-307): 5.14e-125: 393: 31.73		RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00
+	Hs
		545345 PTPRJ_HUMAN (4-307): 5.14e-125: 393: 31.73		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		893944 PTPRJ_HUMAN (4-307): 5.14e-125: 393: 31.73		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		900420 PTPRJ_HUMAN (4-307): 5.14e-125: 393: 31.73		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		436276 PTPRJ_HUMAN (4-307): 5.14e-125: 393: 31.73		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Hs
		892338 PTPRJ_HUMAN (4-307): 5.14e-125: 393: 31.73		RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88
+	Hs
		564498 PTPRJ_HUMAN (4-307): 5.14e-125: 393: 31.73		RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84
+	Hs
		436285 PTPRS_HUMAN (17-276): 1.14e-108: 353: 32.08		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Hs
		564508 PTPRS_HUMAN (17-276): 1.14e-108: 353: 32.08		RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84