HitPredict

Interactor 1: PPIA (P17742)
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) (SP18) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]
Gene: PPIA

Interactor 2: RIGI (Q6Q899)
Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)
Gene: RIGI

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28594325
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 164 Mm			1 926
+	Hs
		321885 PPIA_HUMAN (1-164): 5.74e-91: 263: 96.34		RIGI_HUMAN (1-925): 0: 598: 77.08
+	Mm
		1163205 RBP2_MOUSE (3-164): 9.68e-73: 238: 67.28		RIGI_MOUSE (1-926): 0: 602: 100.00
+	Hs
		923777 PPIA_HUMAN (1-164): 5.74e-91: 263: 96.34		IFIH1_HUMAN (6-923): 7.13e-117: 383: 27.37
+	Sc
		540592 CYPH_YEAST (4-164): 3.2e-86: 251: 64.60		MPH1_YEAST (176-783): 1.22e-83: 292: 17.79
+	Hs
		1271695 PPIE_HUMAN (2-163): 3.8e-89: 263: 66.67		DDX17_HUMAN (459-831): 9.96e-40: 159: 14.39
+	Hs
		571634 PPIE_HUMAN (2-163): 3.8e-89: 263: 66.67		DDX5_HUMAN (511-792): 5.62e-37: 150: 17.24
+	Hs
		133966 PPIA_HUMAN (1-164): 5.74e-91: 263: 96.34		DDX3X_HUMAN (381-767): 3.01e-34: 142: 12.93
+	Hs
		134252 PPIE_HUMAN (2-163): 3.8e-89: 263: 66.67		DDX3X_HUMAN (381-767): 3.01e-34: 142: 12.93
+	Hs
		757552 PPIA_HUMAN (1-164): 5.74e-91: 263: 96.34		IF4A3_HUMAN (239-610): 9.13e-28: 118: 13.71
+	Hs
		757802 PPIE_HUMAN (2-163): 3.8e-89: 263: 66.67		IF4A3_HUMAN (239-610): 9.13e-28: 118: 13.71