Protein: CO2
Complement C2 (C3/C5 convertase) [Cleaved into: Complement C2a; Serine protease complement C2b (EC 3.4.21.43)]

Gene: CO2, C2
Organism: Homo sapiens
Interactions: 15
UniProt ID: P06681

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006508 - proteolysis
GO:0006956 - complement activation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

444673

DAF
Complement decay-accelerating factor

2

14

High-throughput

0.789

High

444675

CO4A
Complement C4-A

2

20

Small-scale

0.778

High

444674

C1S
Complement C1s subcomponent

2

17

Small-scale

0.712

High

444676

CO4B
Complement C4-B

1

20

Small-scale

0.618

High

444677

MUC1
Mucin-1

2

1

High-throughput

0.606

High

444678

STOM
Stomatin

2

1

High-throughput

0.606

High

444682

F209A
Protein FAM209A

2

1

High-throughput

0.606

High

444683

SC11C
Signal peptidase complex catalytic subunit SEC11C

2

1

High-throughput

0.606

High

125802

MASP2
Mannan-binding lectin serine protease 2

1

17

Small-scale

0.575

High

444679

MASP1
Mannan-binding lectin serine protease 1

1

17

Small-scale

0.575

High

230241

CREB3
Cyclic AMP-responsive element-binding protein 3

1

2

High-throughput

0.523

High

444680

NTCP
Hepatic sodium/bile acid cotransporter

2

0

High-throughput

0.316

High

444681

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.316

High

444684

S35C2
Solute carrier family 35 member C2

2

0

High-throughput

0.316

High

444685

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.316

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025