HitPredict

Interactor 1: PYRG1 (P17812)
CTP synthase 1 (EC 6.3.4.2) (CTP synthetase 1) (UTP--ammonia ligase 1)
Gene: CTPS1

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 591 Hs			1 768
+	Hs
		1042625 PYRG2_HUMAN (1-585): 0: 1034: 75.04		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		571007 PYRG1_HUMAN (1-591): 0: 1089: 100.00		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		571004 PYRG1_HUMAN (1-591): 0: 1089: 100.00		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		571005 PYRG1_HUMAN (1-591): 0: 1089: 100.00		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		571040 PYRG1_HUMAN (1-591): 0: 1089: 100.00		CUL5_HUMAN (25-768): 0: 597: 23.77