Interactor 1: EGLN (P17813)
Endoglin (CD antigen CD105)
Gene: ENG
Interactor 2: SMAD1 (Q15797)
Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (JV4-1) (Mad-related protein 1) (SMAD family member 1) (SMAD 1) (Smad1) (hSMAD1) (Transforming growth factor-beta-signaling protein 1) (BSP-1)
Gene: SMAD1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 0.60 | 0.536 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31540324 |
| Identification Methods | affinity chromatography technology, anti bait coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0007179 - transforming growth factor beta receptor signaling pathway GO:0010628 - positive regulation of gene expression GO:0030509 - BMP signaling pathway GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0060348 - bone development |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
