HitPredict

Interactor 1: DDX5 (P17844)
Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68)
Gene: DDX5

Interactor 2: HNRH2 (P55795)
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]
Gene: HNRNPH2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	22365833
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016020 - membrane and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 614 Hs			1 449
+	Hs
		571325 DDX5_HUMAN (1-614): 0: 624: 100.00		HNRH1_HUMAN (1-449): 2.8e-73: 239: 96.21
+	Mm
		193445 Q8BTS0_MOUSE (1-614): 0: 617: 97.89		HNRH1_MOUSE (1-449): 5.42e-73: 238: 95.99
+	Hs
		682917 DDX17_HUMAN (30-612): 0: 534: 66.83		HNRH1_HUMAN (1-449): 2.8e-73: 239: 96.21
+	Hs
		134018 DDX3X_HUMAN (2-556): 9.8e-147: 441: 35.52		PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59
+	Hs
		133858 DDX3X_HUMAN (2-556): 9.8e-147: 441: 35.52		PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29
+	Hs
		571324 DDX5_HUMAN (1-614): 0: 624: 100.00		HNRH3_HUMAN (10-86): 8.49e-10: 62.2: 33.77
+	Hs
		571302 DDX5_HUMAN (1-614): 0: 624: 100.00		NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16
+	Hs
		682642 DDX17_HUMAN (30-612): 0: 534: 66.83		HNRH3_HUMAN (10-86): 8.49e-10: 62.2: 33.77
+	Dm
		580765 DDX17_DROME (2-481): 8.16e-150: 451: 60.87		Q9W0D6_DROME (13-200): 9.78e-15: 78.7: 17.29
+	Hs
		133876 DDX3X_HUMAN (2-556): 9.8e-147: 441: 35.52		NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16