Protein: GLU2B
Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH)

Gene: GLU2B, PRKCSH
Organism: Homo sapiens
Interactions: 226
UniProt ID: P14314

Gene Ontology (top 5):
GO:0001889 - liver development
GO:0005080 - protein kinase C binding
GO:0005509 - calcium ion binding
GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

571434

GANAB
Neutral alpha-glucosidase AB

1

2

Small-scale

0.724

High

171393

S27A2
Long-chain fatty acid transport protein 2

3

1

High-throughput

0.667

High

571469

DEN6A
Protein DENND6A

3

0

High-throughput

0.638

High

571419

KPCZ
Protein kinase C zeta type

2

2

Small-scale

0.618

High

229641

CALU
Calumenin

1

1

High-throughput

0.618

High

571362

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.586

High

534578

BIP
Endoplasmic reticulum chaperone BiP

2

0

High-throughput

0.585

High

571546

COPG1
Coatomer subunit gamma-1

2

0

High-throughput

0.585

High

571465

ZGRF1
5'-3' DNA helicase ZGRF1

3

2

High-throughput

0.585

High

566530

PDIA4
Protein disulfide-isomerase A4

2

3

High-throughput

0.584

High

571499

CALR3
Calreticulin-3

2

3

High-throughput

0.584

High

571369

PPIB
Peptidyl-prolyl cis-trans isomerase B

2

0

High-throughput

0.576

High

571515

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

2

0

High-throughput

0.576

High

571399

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2

2

2

High-throughput

0.558

High

571442

ITSN1
Intersectin-1

1

1

High-throughput

0.536

High

395419

ESR1
Estrogen receptor

2

1

Small-scale

0.534

High

571445

PTPRO
Receptor-type tyrosine-protein phosphatase O

2

3

High-throughput

0.533

High

571477

DOCK8
Dedicator of cytokinesis protein 8

2

1

High-throughput

0.521

High

571501

DOCK7
Dedicator of cytokinesis protein 7

2

1

High-throughput

0.521

High

571410

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.518

High

571372

MK03
Mitogen-activated protein kinase 3

1

0

High-throughput

0.513

High

571392

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

High-throughput

0.513

High

571402

PLAT3
Phospholipase A and acyltransferase 3

1

0

High-throughput

0.513

High

571482

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

0

High-throughput

0.513

High

571395

ARL4D
ADP-ribosylation factor-like protein 4D

1

2

High-throughput

0.494

High

571467

PLCZ1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1

1

0

High-throughput

0.493

High

571474

UN13C
Protein unc-13 homolog C

1

0

High-throughput

0.493

High

571537

CLC4E
C-type lectin domain family 4 member E

1

0

High-throughput

0.493

High

62092

KLRG2
Killer cell lectin-like receptor subfamily G member 2

1

1

High-throughput

0.489

High

161938

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

2

High-throughput

0.489

High

563113

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.489

High

571411

TBA4A
Tubulin alpha-4A chain

1

1

High-throughput

0.489

High

571440

MYLK
Myosin light chain kinase, smooth muscle

1

2

High-throughput

0.489

High

571451

GP107
Protein GPR107

1

1

High-throughput

0.489

High

571466

MYLK4
Myosin light chain kinase family member 4

1

4

High-throughput

0.489

High

571532

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

1

3

High-throughput

0.489

High

217776

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

240642

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

461096

HS90A
Heat shock protein HSP 90-alpha

1

2

High-throughput

0.479

High

465929

CO1A2
Collagen alpha-2(I) chain

1

1

High-throughput

0.479

High

571364

STMN1
Stathmin

1

1

High-throughput

0.479

High

571374

CALR
Calreticulin

1

3

High-throughput

0.479

High

571377

TKT
Transketolase

1

1

High-throughput

0.479

High

571378

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

571380

UFO
Tyrosine-protein kinase receptor UFO

1

3

High-throughput

0.479

High

571386

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

1

High-throughput

0.479

High

571397

GSK3B
Glycogen synthase kinase-3 beta

1

1

High-throughput

0.479

High

571418

NOTC2
Neurogenic locus notch homolog protein 2

1

1

High-throughput

0.479

High

571424

DNJC3
DnaJ homolog subfamily C member 3

1

3

High-throughput

0.479

High

571438

RHG19
Rho GTPase-activating protein 19

1

1

High-throughput

0.479

High

571458

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

2

High-throughput

0.479

High

571470

DJC10
DnaJ homolog subfamily C member 10

1

4

High-throughput

0.479

High

571475

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.479

High

571481

DJB14
DnaJ homolog subfamily B member 14

1

4

High-throughput

0.479

High

571486

TITIN
Titin

1

2

High-throughput

0.479

High

571494

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

571510

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

3

High-throughput

0.479

High

571526

DJB12
DnaJ homolog subfamily B member 12

1

4

High-throughput

0.479

High

571530

DNJB9
DnaJ homolog subfamily B member 9

1

4

High-throughput

0.479

High

571531

DJB11
DnaJ homolog subfamily B member 11

1

1

High-throughput

0.479

High

571539

FND3A
Fibronectin type-III domain-containing protein 3A

1

1

High-throughput

0.479

High

352916

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.458

High

365284

PGK1
Phosphoglycerate kinase 1

1

0

High-throughput

0.458

High

413110

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

571371

PSA4
Proteasome subunit alpha type-4

1

0

High-throughput

0.458

High

571393

HSP13
Heat shock 70 kDa protein 13

1

0

High-throughput

0.458

High

571400

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

571405

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

571423

ANK3
Ankyrin-3

1

0

High-throughput

0.458

High

571478

BBS1
BBSome complex member BBS1

1

0

High-throughput

0.458

High

571493

MYDGF
Myeloid-derived growth factor

1

0

High-throughput

0.458

High

571506

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.458

High

571513

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

0

Small-scale

0.458

High

571529

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.458

High

571533

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

571535

APC7
Anaphase-promoting complex subunit 7

1

0

High-throughput

0.458

High

339642

KLF8
Krueppel-like factor 8

1

1

High-throughput

0.457

High

571376

EPHA8
Ephrin type-A receptor 8

1

3

High-throughput

0.457

High

571509

KLF16
Krueppel-like factor 16

1

1

High-throughput

0.457

High

384100

CO1A1
Collagen alpha-1(I) chain

1

1

Small-scale

0.445

High

429227

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

571401

GPC3
Glypican-3

1

1

High-throughput

0.445

High

571426

S39A6
Zinc transporter ZIP6

1

1

High-throughput

0.445

High

571492

ESR2
Estrogen receptor beta

1

1

High-throughput

0.445

High

543453

VDR
Vitamin D3 receptor

1

1

High-throughput

0.439

High

142809

NFIB
Nuclear factor 1 B-type

1

1

High-throughput

0.437

High

471716

PTPRC
Receptor-type tyrosine-protein phosphatase C

1

3

Small-scale

0.437

High

473760

NFIC
Nuclear factor 1 C-type

1

1

High-throughput

0.437

High

571370

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

3

High-throughput

0.437

High

571375

EPHA2
Ephrin type-A receptor 2

1

3

High-throughput

0.437

High

571382

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

1

High-throughput

0.437

High

571384

BASI
Basigin

1

3

High-throughput

0.437

High

571385

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.437

High

571387

CEAM6
Cell adhesion molecule CEACAM6

1

2

High-throughput

0.437

High

571391

MAP1B
Microtubule-associated protein 1B

1

1

High-throughput

0.437

High

571394

NASP
Nuclear autoantigenic sperm protein

1

1

High-throughput

0.437

High

571414

BASP1
Brain acid soluble protein 1

1

1

High-throughput

0.437

High

571416

EWS
RNA-binding protein EWS

1

2

High-throughput

0.437

High

571427

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.437

High

571432

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

1

High-throughput

0.437

High

571437

GAPD1
GTPase-activating protein and VPS9 domain-containing protein 1

1

2

High-throughput

0.437

High

571446

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

3

High-throughput

0.437

High

571447

TECT1
Tectonic-1

1

1

High-throughput

0.437

High

571450

EPHAA
Ephrin type-A receptor 10

1

3

High-throughput

0.437

High

571453

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

571457

SYNE3
Nesprin-3

1

1

High-throughput

0.437

High

571459

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

571460

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.437

High

571464

GOLI
E3 ubiquitin-protein ligase RNF130

1

1

High-throughput

0.437

High

571480

RIN3
Ras and Rab interactor 3

1

2

High-throughput

0.437

High

571491

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

1

High-throughput

0.437

High

571500

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

5

High-throughput

0.437

High

571503

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

2

High-throughput

0.437

High

571514

RHG39
Rho GTPase-activating protein 39

1

1

High-throughput

0.437

High

571519

DJC18
DnaJ homolog subfamily C member 18

1

3

High-throughput

0.437

High

571527

STMN3
Stathmin-3

1

1

High-throughput

0.437

High

571528

PD1L1
Programmed cell death 1 ligand 1

1

2

High-throughput

0.437

High

571538

TRI33
E3 ubiquitin-protein ligase TRIM33

1

1

High-throughput

0.437

High

571543

TRAF6
TNF receptor-associated factor 6

1

1

High-throughput

0.437

High

571403

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.426

High

571383

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.407

High

571484

S22AH
Solute carrier family 22 member 17

1

1

High-throughput

0.407

High

571536

S39AA
Zinc transporter ZIP10

1

1

High-throughput

0.407

High

169921

AURKA
Aurora kinase A

3

0

High-throughput

0.347

High

278804

PEX14
Peroxisomal membrane protein PEX14

3

0

High-throughput

0.347

High

571396

TSC2
Tuberin

3

0

High-throughput

0.347

High

571449

PREP
Presequence protease, mitochondrial

3

0

High-throughput

0.347

High

571441

EFNB3
Ephrin-B3

2

0

High-throughput

0.328

High

571390

RGS2
Regulator of G-protein signaling 2

2

0

High-throughput

0.323

High

342420

RPP29
Ribonuclease P protein subunit p29

2

0

High-throughput

0.318

High

571428

TBB3
Tubulin beta-3 chain

2

0

High-throughput

0.318

High

571472

FCSK
L-fucose kinase

2

0

High-throughput

0.318

High

571455

SPG17
Sperm-associated antigen 17

2

0

High-throughput

0.313

High

559854

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

2

0

High-throughput

0.305

High

571443

EZH2
Histone-lysine N-methyltransferase EZH2

2

0

High-throughput

0.305

High

571398

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.282

High

571461

GET4
Golgi to ER traffic protein 4 homolog

1

0

High-throughput

0.282

High

571516

GBA3
Cytosolic beta-glucosidase

1

0

High-throughput

0.282

High

361097

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.279

Low

479314

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.279

Low

571363

H2AX
Histone H2AX

1

0

High-throughput

0.279

Low

571454

IN80C
INO80 complex subunit C

1

0

High-throughput

0.279

Low

571479

NEUA
N-acylneuraminate cytidylyltransferase

1

0

High-throughput

0.279

Low

571483

PHOP1
Phosphoethanolamine/phosphocholine phosphatase

1

0

High-throughput

0.279

Low

571489

MY18A
Unconventional myosin-XVIIIa

1

0

High-throughput

0.279

Low

571495

CSTOS
Protein CUSTOS

1

0

High-throughput

0.279

Low

571502

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.279

Low

571507

CMS1
Protein CMSS1

1

0

High-throughput

0.279

Low

571508

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

0

High-throughput

0.279

Low

571512

YTHD1
YTH domain-containing family protein 1

1

0

High-throughput

0.279

Low

571518

NOL6
Nucleolar protein 6

1

0

High-throughput

0.279

Low

571523

PDRG1
p53 and DNA damage-regulated protein 1

1

0

High-throughput

0.279

Low

571545

HCFC2
Host cell factor 2

1

0

High-throughput

0.279

Low

62022

LRRD1
Leucine-rich repeat and death domain-containing protein 1

1

0

High-throughput

0.269

Low

547408

DMD
Dystrophin

1

0

High-throughput

0.269

Low

571373

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.269

Low

571404

PRD15
PR domain zinc finger protein 15

1

0

High-throughput

0.269

Low

571444

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.269

Low

571462

NANGN
NANOG neighbor homeobox

1

0

High-throughput

0.269

Low

571463

KIF27
Kinesin-like protein KIF27

1

0

High-throughput

0.269

Low

571542

TGRM1
TOG array regulator of axonemal microtubules protein 1

1

0

High-throughput

0.269

Low

105244

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

140727

NOP56
Nucleolar protein 56

1

0

High-throughput

0.249

Low

169418

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

0

High-throughput

0.249

Low

326293

SCAF4
SR-related and CTD-associated factor 4

1

0

High-throughput

0.249

Low

411287

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

459432

PROF1
Profilin-1

1

0

High-throughput

0.249

Low

464105

TPM2
Tropomyosin beta chain

1

0

High-throughput

0.249

Low

516080

INAM2
Putative transmembrane protein INAFM2

1

0

High-throughput

0.249

Low

565756

EF2
Elongation factor 2

1

0

High-throughput

0.249

Low

571365

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.249

Low

571366

EGR1
Early growth response protein 1

1

0

High-throughput

0.249

Low

571367

PGAM1
Phosphoglycerate mutase 1

1

0

High-throughput

0.249

Low

571368

PTMS
Parathymosin

1

0

High-throughput

0.249

Low

571379

PEBP1
Phosphatidylethanolamine-binding protein 1

1

0

High-throughput

0.249

Low

571381

H2B1B
Histone H2B type 1-B

1

0

High-throughput

0.249

Low

571388

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.249

Low

571406

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

0

High-throughput

0.249

Low

571407

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.249

Low

571408

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.249

Low

571409

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

571412

NOP14
Nucleolar protein 14

1

0

High-throughput

0.249

Low

571413

ELF3
ETS-related transcription factor Elf-3

1

0

High-throughput

0.249

Low

571415

FKBP3
Peptidyl-prolyl cis-trans isomerase FKBP3

1

0

High-throughput

0.249

Low

571417

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.249

Low

571421

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

0

High-throughput

0.249

Low

571422

TRI26
Tripartite motif-containing protein 26

1

0

Small-scale

0.249

Low

571425

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

0

High-throughput

0.249

Low

571429

CUL3
Cullin-3

1

0

High-throughput

0.249

Low

571430

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.249

Low

571431

DX39B
Spliceosome RNA helicase DDX39B

1

0

Small-scale

0.249

Low

571433

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

571435

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.249

Low

571436

CUL7
Cullin-7

1

0

High-throughput

0.249

Low

571439

DLGP5
Disks large-associated protein 5

1

0

High-throughput

0.249

Low

571452

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

571456

CD109
CD109 antigen

1

0

High-throughput

0.249

Low

571468

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.249

Low

571471

CE57L
Centrosomal protein CEP57L1

1

0

High-throughput

0.249

Low

571473

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.249

Low

571476

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.249

Low

571487

TM131
Transmembrane protein 131

1

0

High-throughput

0.249

Low

571488

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.249

Low

571490

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.249

Low

571496

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.249

Low

571498

LRIG1
Leucine-rich repeats and immunoglobulin-like domains protein 1

1

0

High-throughput

0.249

Low

571504

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.249

Low

571517

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

0

Small-scale

0.249

Low

571520

PLRKT
Plasminogen receptor

1

0

High-throughput

0.249

Low

571521

DDX21
Nucleolar RNA helicase 2

1

0

High-throughput

0.249

Low

571522

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.249

Low

571524

T106B
Transmembrane protein 106B

1

0

High-throughput

0.249

Low

571525

INT7
Integrator complex subunit 7

1

0

High-throughput

0.249

Low

571534

ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

0.249

Low

571540

TMA7
Translation machinery-associated protein 7

1

0

High-throughput

0.249

Low

571541

FBX7
F-box only protein 7

1

0

Small-scale

0.249

Low

571544

RBM8A
RNA-binding protein 8A

1

0

High-throughput

0.249

Low

571505

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.238

Low

528986

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.232

Low

571389

S26A3
Chloride anion exchanger

1

0

High-throughput

0.232

Low

571420

SLC31
Amino acid transporter heavy chain SLC3A1

1

0

High-throughput

0.232

Low

571448

LETM2
LETM1 domain-containing protein LETM2, mitochondrial

1

0

High-throughput

0.232

Low

571485

S38A5
Sodium-coupled neutral amino acid transporter 5

1

0

High-throughput

0.232

Low

571497

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.232

Low

571511

S4A5
Electrogenic sodium bicarbonate cotransporter 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025