HitPredict

Interactor 1: HS71B (P17879)
Heat shock 70 kDa protein 1B (Heat shock 70 kDa protein 1) (HSP70.1)
Gene: Hspa1b

Interactor 2: BAG3 (Q9JLV1)
BAG family molecular chaperone regulator 3 (BAG-3) (Bcl-2-associated athanogene 3) (Bcl-2-binding protein Bis)
Gene: BAG3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11527400
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAG~HSP70
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043066 - negative regulation of apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 642 Mm			1 577
+	Mm
		926166 HSP7C_MOUSE (1-642): 0: 951: 83.90		BAG3_MOUSE (1-577): 0: 849: 100.00
+	Hs
		324256 HS71L_HUMAN (2-642): 0: 965: 87.21		BAG3_HUMAN (1-577): 0: 729: 83.31
+	Hs
		324216 HSP76_HUMAN (3-642): 0: 953: 81.41		BAG3_HUMAN (1-577): 0: 729: 83.31
+	Hs
		324195 HSP7C_HUMAN (1-642): 0: 952: 83.75		BAG3_HUMAN (1-577): 0: 729: 83.31
+	Hs
		324190 HS71A_HUMAN (1-642): 0: 951: 94.24		BAG3_HUMAN (1-577): 0: 729: 83.31
+	Hs
		324435 Q53FC7_HUMAN (3-642): 0: 949: 81.09		BAG3_HUMAN (1-577): 0: 729: 83.31
+	Mm
		571864 HS71B_MOUSE (1-642): 0: 966: 100.00		BAG4_MOUSE (386-504): 1.7e-39: 151: 47.90
+	Hs
		314010 HS71L_HUMAN (2-642): 0: 965: 87.21		BAG4_HUMAN (386-504): 6.82e-36: 141: 45.38
+	Hs
		314001 HSP76_HUMAN (3-642): 0: 953: 81.41		BAG4_HUMAN (386-504): 6.82e-36: 141: 45.38
+	Hs
		313996 HSP7C_HUMAN (1-642): 0: 952: 83.75		BAG4_HUMAN (386-504): 6.82e-36: 141: 45.38
+	Hs
		314060 Q53FC7_HUMAN (3-642): 0: 949: 81.09		BAG4_HUMAN (386-504): 6.82e-36: 141: 45.38
+	Dm
		65607 HSP72_DROME (6-642): 0: 949: 75.15		A8JNS4_DROME (401-503): 9.74e-27: 116: 30.63
+	Dm
		65599 HSP71_DROME (6-642): 0: 947: 74.88		A8JNS4_DROME (401-503): 9.74e-27: 116: 30.63
+	Dm
		947905 HSP70_DROME (6-642): 0: 947: 74.88		Q9VU81_DROME (401-503): 8.63e-27: 116: 30.63
+	Hs
		714093 HS71L_HUMAN (2-642): 0: 965: 87.21		BAG5_HUMAN (423-503): 3.96e-17: 86: 43.21
+	Mm
		571863 HS71B_MOUSE (1-642): 0: 966: 100.00		BAG5_MOUSE (419-503): 1.69e-16: 84.1: 42.35
+	Hs
		564206 HSP76_HUMAN (3-642): 0: 953: 81.41		BAG5_HUMAN (423-503): 3.96e-17: 86: 43.21
+	Hs
		504937 HSP7C_HUMAN (1-642): 0: 952: 83.75		BAG5_HUMAN (423-503): 3.96e-17: 86: 43.21
+	Mm
		926151 HSP7C_MOUSE (1-642): 0: 951: 83.90		BAG5_MOUSE (419-503): 1.69e-16: 84.1: 42.35
+	Hs
		1120596 Q53FC7_HUMAN (3-642): 0: 949: 81.09		BAG5_HUMAN (423-503): 3.96e-17: 86: 43.21