HitPredict

Interactor 1: LEG3 (P17931)
Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen)
Gene: LGALS3

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16393961
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0045087 - innate immune response
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 250 Hs			1 522
+	Mm
		936254 Q8C253_MOUSE (1-250): 6.8e-82: 247: 78.87		TRAF6_MOUSE (1-522): 5.7e-141: 418: 87.93
+	Hs
		572488 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		TRI17_HUMAN (58-408): 7.59e-43: 160: 11.86
+	Hs
		572401 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		TRI22_HUMAN (56-361): 5.96e-39: 150: 15.51
+	Hs
		572447 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		TRIM6_HUMAN (56-403): 5.03e-39: 150: 12.97
+	Hs
		572350 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		TRI26_HUMAN (61-410): 2.85e-38: 149: 14.59
+	Hs
		572448 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		TRIM5_HUMAN (56-315): 8.46e-38: 147: 16.11
+	Hs
		814949 LEG7_HUMAN (115-247): 3.1e-45: 149: 35.04		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		119373 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		301562 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		121234 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		TRI17_HUMAN (58-408): 7.59e-43: 160: 11.86
+	Hs
		536943 PPL13_HUMAN (112-248): 3.08e-39: 134: 27.08		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		121188 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		TRI22_HUMAN (56-361): 5.96e-39: 150: 15.51
+	Hs
		121210 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		TRIM6_HUMAN (56-403): 5.03e-39: 150: 12.97
+	Hs
		121211 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		TRIM5_HUMAN (56-315): 8.46e-38: 147: 16.11
+	Hs
		1232885 PPL13_HUMAN (112-248): 3.08e-39: 134: 27.08		LNX2_HUMAN (58-183): 1.56e-11: 69.1: 21.88
+	Hs
		1252358 PPL13_HUMAN (112-248): 3.08e-39: 134: 27.08		LNX1_HUMAN (58-183): 2.59e-11: 68.3: 19.84