Protein: ACM5
Muscarinic acetylcholine receptor M5

Gene: ACM5, CHRM5
Organism: Homo sapiens
Interactions: 40
UniProt ID: P08912

Gene Ontology (top 5):
GO:0001696 - gastric acid secretion
GO:0004435 - phosphatidylinositol-4,5-bisphosphate phospholipase C activity
GO:0005886 - plasma membrane
GO:0007187 - G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007197 - adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

477153

ACM3
Muscarinic acetylcholine receptor M3

1

17

Small-scale

0.665

High

477163

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

4

High-throughput

0.625

High

477179

NLE1
Notchless protein homolog 1

1

0

High-throughput

0.584

High

270616

ATP9A
Probable phospholipid-transporting ATPase IIA

1

3

High-throughput

0.541

High

477152

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

10

High-throughput

0.541

High

477154

CD82
CD82 antigen

1

14

High-throughput

0.541

High

477155

HLAF
HLA class I histocompatibility antigen, alpha chain F

1

1

High-throughput

0.541

High

477156

SYUA
Alpha-synuclein

1

5

High-throughput

0.541

High

477157

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

3

High-throughput

0.541

High

477167

MSMO1
Methylsterol monooxygenase 1

1

4

High-throughput

0.541

High

477168

RTN1
Reticulon-1

1

5

High-throughput

0.541

High

477177

E41L1
Band 4.1-like protein 1

1

3

High-throughput

0.541

High

477183

SC5A6
Sodium-dependent multivitamin transporter

1

1

High-throughput

0.541

High

477160

CAV1
Caveolin-1

1

4

High-throughput

0.536

High

477161

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.518

High

477182

GTR6
Solute carrier family 2, facilitated glucose transporter member 6

1

0

High-throughput

0.518

High

477158

RGS7
Regulator of G-protein signaling 7

1

12

Small-scale

0.501

High

67423

GOG8A
Golgin subfamily A member 8A

1

5

High-throughput

0.494

High

337288

CXB6
Gap junction beta-6 protein

1

5

High-throughput

0.494

High

344449

STR3N
STARD3 N-terminal-like protein

1

1

High-throughput

0.494

High

477159

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.494

High

477173

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

1

5

High-throughput

0.494

High

477181

T161A
Transmembrane protein 161A

1

1

High-throughput

0.494

High

477162

TRI26
Tripartite motif-containing protein 26

1

1

High-throughput

0.489

High

477172

ARL10
ADP-ribosylation factor-like protein 10

1

9

High-throughput

0.489

High

477180

TM160
Transmembrane protein 160

1

1

High-throughput

0.489

High

477164

SNX1
Sorting nexin-1

1

4

Small-scale

0.437

High

477169

GASP1
G-protein coupled receptor-associated sorting protein 1

1

14

Small-scale

0.437

High

477170

PR15B
Protein phosphatase 1 regulatory subunit 15B

1

1

High-throughput

0.407

High

219840

SMAD6
Mothers against decapentaplegic homolog 6

1

0

High-throughput

0.282

High

271194

ASTN2
Astrotactin-2

1

0

High-throughput

0.282

High

464354

ERCC1
DNA excision repair protein ERCC-1

1

0

High-throughput

0.282

High

477151

MYH7
Myosin-7

1

0

High-throughput

0.282

High

477165

PEBB
Core-binding factor subunit beta

1

0

High-throughput

0.282

High

477171

NPAS3
Neuronal PAS domain-containing protein 3

1

0

High-throughput

0.282

High

477175

EPC1
Enhancer of polycomb homolog 1

1

0

High-throughput

0.282

High

477176

SPNS1
Protein spinster homolog 1

1

0

High-throughput

0.282

High

477178

TSSP
Thymus-specific serine protease

1

0

High-throughput

0.282

High

477166

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.279

Low

477174

K0232
Uncharacterized protein KIAA0232

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025