HitPredict

Interactor 1: PRS6A (P17980)
26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1)
Gene: PSMC3

Interactor 2: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 33961781, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 439 Hs			1 607
+	Hs
		875022 TERA_HUMAN (162-434): 9.21e-77: 256: 35.17		A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00
+	Hs
		1146624 AFG2A_HUMAN (182-435): 3.65e-68: 234: 35.32		A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00
+	Hs
		1089451 AFG2A_HUMAN (182-435): 3.65e-68: 234: 35.32		Q17RG0_HUMAN (28-607): 1.28e-156: 463: 100.00
+	Hs
		792951 PRS8_HUMAN (65-437): 1.93e-126: 373: 44.39		LIS1_HUMAN (99-438): 6.8e-50: 180: 14.98
+	Hs
		792936 PRS6B_HUMAN (8-438): 1.04e-118: 354: 37.59		LIS1_HUMAN (99-438): 6.8e-50: 180: 14.98
+	Hs
		906981 PRS8_HUMAN (65-437): 1.93e-126: 373: 44.39		GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62
+	Hs
		572915 PRS6A_HUMAN (1-439): 1.23e-136: 401: 100.00		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Hs
		875215 TERA_HUMAN (162-434): 9.21e-77: 256: 35.17		SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48
+	Hs
		903081 PRS8_HUMAN (65-437): 1.93e-126: 373: 44.39		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Hs
		798631 PRS6B_HUMAN (8-438): 1.04e-118: 354: 37.59		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Sc
		744630 PRS4_YEAST (122-431): 4.87e-102: 312: 50.65		TAF5_YEAST (129-424): 1.16e-19: 95.5: 9.33
+	Mm
		967679 TERA_MOUSE (162-434): 9.21e-77: 256: 35.17		A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25
+	Sc
		636597 CDC48_YEAST (144-419): 9.98e-80: 265: 37.32		TAF5_YEAST (129-424): 1.16e-19: 95.5: 9.33
+	Hs
		874768 TERA_HUMAN (162-434): 9.21e-77: 256: 35.17		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45