HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21319273
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 556 Hs			1 298
+	Hs
		625228 TCPG_HUMAN (5-550): 0: 593: 33.03		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		414725 TCPA_HUMAN (1-556): 0: 630: 100.00		CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90
+	Hs
		625579 TCPH_HUMAN (1-545): 0: 566: 34.84		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		573225 TCPA_HUMAN (1-556): 0: 630: 100.00		CDK5_HUMAN (1-292): 1.62e-138: 394: 59.39
+	Hs
		625220 TCPE_HUMAN (4-530): 0: 550: 31.96		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		826623 TCPG_HUMAN (5-550): 0: 593: 33.03		CDK5_HUMAN (1-292): 1.62e-138: 394: 59.39
+	Hs
		415042 TCPH_HUMAN (1-545): 0: 566: 34.84		CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90
+	Hs
		960322 TCPH_HUMAN (1-545): 0: 566: 34.84		CDK5_HUMAN (1-292): 1.62e-138: 394: 59.39
+	Hs
		414817 TCPE_HUMAN (4-530): 0: 550: 31.96		CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90
+	Hs
		821173 TCPE_HUMAN (4-530): 0: 550: 31.96		CDK5_HUMAN (1-292): 1.62e-138: 394: 59.39
+	Sc
		339390 TCPA_YEAST (4-542): 0: 558: 62.57		CDK1_YEAST (1-288): 3.57e-132: 378: 62.12
+	Sc
		339699 TCPH_YEAST (10-531): 1.74e-87: 282: 35.10		CDK1_YEAST (1-288): 3.57e-132: 378: 62.12