HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	14532270, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0016887 - ATP hydrolysis activity GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 556 Hs			1 375
+	Hs
		826692 TCPG_HUMAN (5-550): 0: 593: 33.03		ACTBL_HUMAN (2-375): 0: 735: 91.71
+	Hs
		1122486 TCPH_HUMAN (1-545): 0: 566: 34.84		ACTBL_HUMAN (2-375): 0: 735: 91.71
+	Hs
		821244 TCPE_HUMAN (4-530): 0: 550: 31.96		ACTBL_HUMAN (2-375): 0: 735: 91.71
+	Hs
		573210 TCPA_HUMAN (1-556): 0: 630: 100.00		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		573212 TCPA_HUMAN (1-556): 0: 630: 100.00		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		826593 TCPG_HUMAN (5-550): 0: 593: 33.03		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		826609 TCPG_HUMAN (5-550): 0: 593: 33.03		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		826611 TCPG_HUMAN (5-550): 0: 593: 33.03		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		891991 TCPH_HUMAN (1-545): 0: 566: 34.84		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		929984 TCPH_HUMAN (1-545): 0: 566: 34.84		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		932351 TCPH_HUMAN (1-545): 0: 566: 34.84		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		821144 TCPE_HUMAN (4-530): 0: 550: 31.96		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		821160 TCPE_HUMAN (4-530): 0: 550: 31.96		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Sc
		519982 TCPA_YEAST (4-542): 0: 558: 62.57		ACT_YEAST (1-375): 0: 591: 88.80
+	Sc
		760791 TCPG_YEAST (1-538): 0: 552: 29.20		ACT_YEAST (1-375): 0: 591: 88.80
+	Hs
		821162 TCPE_HUMAN (4-530): 0: 550: 31.96		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		821163 TCPE_HUMAN (4-530): 0: 550: 31.96		ACTS_HUMAN (2-375): 0: 592: 93.58
+	Hs
		821155 TCPE_HUMAN (4-530): 0: 550: 31.96		ACTA_HUMAN (2-375): 0: 591: 94.12
+	Sc
		792394 TCPH_YEAST (10-531): 1.74e-87: 282: 35.10		ACT_YEAST (1-375): 0: 591: 88.80