Protein: KPYM
Pyruvate kinase PKM (EC 2.7.1.40) (Pyruvate kinase muscle isozyme) (Threonine-protein kinase PKM2) (EC 2.7.11.1) (Tyrosine-protein kinase PKM2) (EC 2.7.10.2)

Gene: KPYM, Pkm
Organism: Mus musculus
Interactions: 45
UniProt ID: P52480

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0001917 - photoreceptor inner segment
GO:0003713 - transcription coactivator activity
GO:0003729 - mRNA binding
GO:0004713 - protein tyrosine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

629206

PO5F1
POU domain, class 5, transcription factor 1

1

3

Small-scale

0.561

High

108536

G3X9H5
Huntingtin

2

3

High-throughput

0.533

High

912294

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

2

2

High-throughput

0.521

High

912314

NPHP1
Nephrocystin-1

1

0

High-throughput

0.513

High

59589

A2AM57
Inversin

1

2

High-throughput

0.489

High

912286

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

3

Small-scale

0.479

High

912287

TRAF6
TNF receptor-associated factor 6

1

9

Small-scale

0.479

High

912290

KPCZ
Protein kinase C zeta type

1

1

Small-scale

0.479

High

912292

Q3UJF1
Histone deacetylase

1

6

High-throughput

0.479

High

912293

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

1

High-throughput

0.479

High

912295

HIF1A
Hypoxia-inducible factor 1-alpha

1

3

Small-scale

0.479

High

912297

TFE3
Transcription factor E3

1

1

High-throughput

0.479

High

912302

TAOK2
Serine/threonine-protein kinase TAO2

1

2

High-throughput

0.479

High

912304

FACD2
Fanconi anemia group D2 protein homolog

1

1

High-throughput

0.479

High

912307

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.479

High

912309

EED
Polycomb protein EED

1

1

High-throughput

0.479

High

912285

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

0

High-throughput

0.458

High

912291

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.458

High

912303

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.458

High

912306

GEPH
Gephyrin [Includes: Molybdopterin adenylyltransferase

1

0

High-throughput

0.458

High

912310

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

912313

ITA2B
Integrin alpha-IIb

1

1

High-throughput

0.457

High

912288

CASP3
Caspase-3

1

2

Small-scale

0.445

High

912289

CASP7
Caspase-7

1

2

Small-scale

0.445

High

912298

Q6AXH7
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.445

High

912315

HDAC5
Histone deacetylase 5

1

6

High-throughput

0.445

High

912301

NEB2
Neurabin-2

1

4

High-throughput

0.437

High

912311

NRX1A
Neurexin-1

1

2

High-throughput

0.437

High

912312

Q9D2V3
Progranulin

1

1

High-throughput

0.437

High

912300

RAB35
Ras-related protein Rab-35

1

0

High-throughput

0.426

High

59465

A2AKD7
Alpha-1-syntrophin

1

3

High-throughput

0.407

High

205716

RB33B
Ras-related protein Rab-33B

1

1

High-throughput

0.407

High

770550

RAB21
Ras-related protein Rab-21

1

1

High-throughput

0.407

High

844152

HD
Huntingtin

1

3

High-throughput

0.407

High

398181

CFAD
Complement factor D

1

0

High-throughput

0.249

Low

727588

SC6A1
Sodium- and chloride-dependent GABA transporter 1

1

0

High-throughput

0.249

Low

912299

Q6GTZ3
Idb1 protein

1

0

Small-scale

0.249

Low

912305

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

0

High-throughput

0.249

Low

912308

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.249

Low

59845

CMAP2
Ciliary microtubule-associated protein 2

1

0

Small-scale

0.238

Low

424614

ANF
Natriuretic peptides A

1

0

High-throughput

0.238

Low

770630

RAB18
Ras-related protein Rab-18

1

0

High-throughput

0.232

Low

770645

RAB19
Ras-related protein Rab-19

1

0

High-throughput

0.232

Low

905786

CAV3
Caveolin-3

1

0

High-throughput

0.232

Low

912296

DLG4
Disks large homolog 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025