HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	25342745, 28514442, 27705803, 33961781, 37689310, 35016035
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 556 Hs			1 342
+	Hs
		826600 TCPG_HUMAN (5-550): 0: 593: 33.03		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		573279 TCPA_HUMAN (1-556): 0: 630: 100.00		RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51
+	Hs
		134767 TCPA_HUMAN (1-556): 0: 630: 100.00		PEX7_HUMAN (20-341): 1.26e-56: 188: 18.41
+	Hs
		573496 TCPA_HUMAN (1-556): 0: 630: 100.00		SC31B_HUMAN (23-336): 4.36e-52: 187: 17.38
+	Hs
		573412 TCPA_HUMAN (1-556): 0: 630: 100.00		SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66
+	Hs
		134772 TCPG_HUMAN (5-550): 0: 593: 33.03		PEX7_HUMAN (20-341): 1.26e-56: 188: 18.41
+	Hs
		826904 TCPG_HUMAN (5-550): 0: 593: 33.03		SC31B_HUMAN (23-336): 4.36e-52: 187: 17.38
+	At
		186921 TCPA_ARATH (7-541): 0: 579: 66.17		MSI1_ARATH (17-342): 3.99e-58: 195: 15.00
+	Hs
		573371 TCPA_HUMAN (1-556): 0: 630: 100.00		POC1A_HUMAN (2-204): 1.46e-29: 118: 18.72
+	Hs
		573201 TCPA_HUMAN (1-556): 0: 630: 100.00		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		573384 TCPA_HUMAN (1-556): 0: 630: 100.00		POC1B_HUMAN (6-194): 2.26e-21: 96.4: 8.40
+	Hs
		573445 TCPA_HUMAN (1-556): 0: 630: 100.00		GRWD1_HUMAN (206-342): 9.29e-18: 85.5: 17.61
+	Hs
		826772 TCPG_HUMAN (5-550): 0: 593: 33.03		POC1A_HUMAN (2-204): 1.46e-29: 118: 18.72
+	Hs
		826601 TCPG_HUMAN (5-550): 0: 593: 33.03		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		573346 TCPA_HUMAN (1-556): 0: 630: 100.00		WDR5B_HUMAN (2-148): 2.99e-13: 71.4: 10.74
+	At
		660214 TCPA_ARATH (7-541): 0: 579: 66.17		PEX7_ARATH (124-342): 7.3e-31: 120: 16.23
+	Hs
		792942 TCPG_HUMAN (5-550): 0: 593: 33.03		LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82
+	Hs
		826784 TCPG_HUMAN (5-550): 0: 593: 33.03		POC1B_HUMAN (6-194): 2.26e-21: 96.4: 8.40
+	Hs
		826847 TCPG_HUMAN (5-550): 0: 593: 33.03		GRWD1_HUMAN (206-342): 9.29e-18: 85.5: 17.61
+	Hs
		826748 TCPG_HUMAN (5-550): 0: 593: 33.03		WDR5B_HUMAN (2-148): 2.99e-13: 71.4: 10.74