HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: PP2AB (P62714)
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16)
Gene: PPP2CB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	26496610, 18782753, 19156129
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 556 Hs			1 309
+	Hs
		573211 TCPA_HUMAN (1-556): 0: 630: 100.00		PP2AA_HUMAN (1-309): 0: 533: 97.41
+	Hs
		573192 TCPA_HUMAN (1-556): 0: 630: 100.00		PP4C_HUMAN (4-309): 0: 511: 64.50
+	Hs
		826610 TCPG_HUMAN (5-550): 0: 593: 33.03		PP2AA_HUMAN (1-309): 0: 533: 97.41
+	Hs
		826603 TCPG_HUMAN (5-550): 0: 593: 33.03		PP2AB_HUMAN (1-309): 0: 532: 100.00
+	Hs
		826591 TCPG_HUMAN (5-550): 0: 593: 33.03		PP4C_HUMAN (4-309): 0: 511: 64.50
+	Hs
		930969 TCPH_HUMAN (1-545): 0: 566: 34.84		PP2AA_HUMAN (1-309): 0: 533: 97.41
+	Hs
		915267 TCPH_HUMAN (1-545): 0: 566: 34.84		PP2AB_HUMAN (1-309): 0: 532: 100.00
+	Sc
		618836 TCPG_YEAST (1-538): 0: 552: 29.20		PP2A2_YEAST (9-309): 0: 531: 76.08
+	Hs
		821161 TCPE_HUMAN (4-530): 0: 550: 31.96		PP2AA_HUMAN (1-309): 0: 533: 97.41
+	Hs
		821154 TCPE_HUMAN (4-530): 0: 550: 31.96		PP2AB_HUMAN (1-309): 0: 532: 100.00
+	Sc
		519896 TCPA_YEAST (4-542): 0: 558: 62.57		PP2A1_YEAST (7-309): 0: 519: 74.92
+	Hs
		890997 TCPH_HUMAN (1-545): 0: 566: 34.84		PP4C_HUMAN (4-309): 0: 511: 64.50
+	Sc
		618772 TCPG_YEAST (1-538): 0: 552: 29.20		PP2A1_YEAST (7-309): 0: 519: 74.92
+	Hs
		821143 TCPE_HUMAN (4-530): 0: 550: 31.96		PP4C_HUMAN (4-309): 0: 511: 64.50
+	Sc
		519892 TCPA_YEAST (4-542): 0: 558: 62.57		PP11_YEAST (11-309): 4.65e-139: 397: 58.03
+	Sc
		594322 TCPG_YEAST (1-538): 0: 552: 29.20		PP11_YEAST (11-309): 4.65e-139: 397: 58.03
+	Sc
		618845 TCPH_YEAST (10-531): 1.74e-87: 282: 35.10		PP2A2_YEAST (9-309): 0: 531: 76.08
+	Sc
		618781 TCPH_YEAST (10-531): 1.74e-87: 282: 35.10		PP2A1_YEAST (7-309): 0: 519: 74.92
+	Sc
		594334 TCPH_YEAST (10-531): 1.74e-87: 282: 35.10		PP11_YEAST (11-309): 4.65e-139: 397: 58.03