HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005874 - microtubule GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 556 Hs			1 451
+	Hs
		573448 TCPA_HUMAN (1-556): 0: 630: 100.00		TBA1C_HUMAN (1-451): 0: 728: 98.00
+	Hs
		573214 TCPA_HUMAN (1-556): 0: 630: 100.00		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		573332 TCPA_HUMAN (1-556): 0: 630: 100.00		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		428007 TCPA_HUMAN (1-556): 0: 630: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		573215 TCPA_HUMAN (1-556): 0: 630: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		826850 TCPG_HUMAN (5-550): 0: 593: 33.03		TBA1C_HUMAN (1-451): 0: 728: 98.00
+	Hs
		826613 TCPG_HUMAN (5-550): 0: 593: 33.03		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		826612 TCPG_HUMAN (5-550): 0: 593: 33.03		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		826733 TCPG_HUMAN (5-550): 0: 593: 33.03		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		1306647 TCPH_HUMAN (1-545): 0: 566: 34.84		TBA1C_HUMAN (1-451): 0: 728: 98.00
+	Hs
		826723 TCPG_HUMAN (5-550): 0: 593: 33.03		TBA3E_HUMAN (1-440): 0: 700: 96.59
+	Mm
		933713 TCPH_MOUSE (1-551): 0: 577: 35.18		TBA1A_MOUSE (1-440): 0: 715: 99.55
+	Hs
		826614 TCPG_HUMAN (5-550): 0: 593: 33.03		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		933582 TCPH_HUMAN (1-545): 0: 566: 34.84		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		933325 TCPH_HUMAN (1-545): 0: 566: 34.84		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		1175131 TCPH_HUMAN (1-545): 0: 566: 34.84		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		821164 TCPE_HUMAN (4-530): 0: 550: 31.96		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		1161212 TCPH_HUMAN (1-545): 0: 566: 34.84		TBA3E_HUMAN (1-440): 0: 700: 96.59
+	Hs
		428388 TCPH_HUMAN (1-545): 0: 566: 34.84		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		933944 TCPH_HUMAN (1-545): 0: 566: 34.84		TBB4B_HUMAN (1-437): 0: 697: 40.96